Silver proteinate

Silver proteinate (brand name: Protargol) is used in electron microscopy with periodic acid and thiocarbohydrazide or thiosemicarbohydrazide as a positive stain for carbohydrates such as glycogen. It can also be used for light microscopy to stain nerve tissue. It is normally available as 8% silver in combination with albumin.[1]

Staining ciliates with silver proteinate can reveal the infraciliature, an important character for identification of ciliates. Hundreds of ciliate species have been discovered using Protargol staining.[2]

Because of its bactericidal properties it was used to treat gonorrhea before the discovery of antibiotics. The inventor of the first silver protein formulation was Arthur Eichengrün, a German chemist working for Bayer. It was introduced for therapeutic use in 1897.[3][4]

See also

References

  1. ^ Silver proteinate at Sigma-Aldrich
  2. ^ Ji, Daode; Wang, Yunfeng (2018). "An Optimized Protocol of Protargol Staining for Ciliated Protozoa". Journal of Eukaryotic Microbiology. 65 (5): 705–708. doi:10.1111/jeu.12515. PMID 29532600. S2CID 3839382.
  3. ^ Vaupel, E. (2005), Arthur Eichengrün—Tribute to a Forgotten Chemist, Entrepreneur, and German Jew Angew. Chem. Int. Ed., 44: 3344–3355. doi: 10.1002/anie.200462959
  4. ^ State Medical Examining and Licensing Boards A Handbook of Useful Drugs: Protargol 1913 Press Of The American Medical Association (hosted on: chestofbooks.com)

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.