SSC may refer to:

• Sydney Secondary College, a public school in Sydney, Australia
• St Stanislaus' College, Bathurst, New South Wales
• Santa Sabina College, Strathfield, New South Wales
• Saint Stephen's College, Coomera, Queensland
• Saint Scholastica's College, Australia

• Saint Stanislaus College, a high school in Bay St. Louis, Mississippi
• Salem State University, a public college in Salem, Massachusetts
• Seminole State College (Oklahoma), a public college in Seminole, Oklahoma
• Seminole State College of Florida, a public college in Seminole County, Florida
• South Seattle College, a two-year public college in Seattle, Washington
• South Suburban College, a community college in South Holland, Illinois

• San Sebastian College – Recoletos in Manila, Philippines
• St. Scholastica's College, Manila, Philippines
• St Stephen's College, Hong Kong, in Stanley, Hong Kong Island
• St. Stephen's Girls' College, Hong Kong, in Pok Fu Lam, Hong Kong Island

• Student selected components, optional elements in the syllabus of UK medical schools
• Secondary School Certificate, the certificate given to students graduating from a secondary school in India, Pakistan or Bangladesh
• Secondary School Leaving Certificate examination

• Shanghai Supercomputer Center, a high-performance computing service provider
• Shared services center, outsourcing
• SSC North America, an automobile manufacturer
• Specialized System Consultants, a private media company
• Swedish Space Corporation, a Swedish government-owned company
• Southern Star Central Gas Pipeline, based in Owensboro, KY

• Saudi Space Commission, government agency of Saudi Arabia
• Secretaria de Seguridad Ciudadana, armed law enforcement agency in Mexico City
• Shared Services Canada
• Space Systems Command, the acquisition, research and development, and launch command of the United States Space Force
• Staff Selection Commission, conducts entry exams for Indian Government staff
• State Security Council of apartheid South Africa
• State Services Commission, oversees public sector performance in New Zealand
• Swiss Science Council, independent scientific advisory body of the Federal Council of Switzerland
• US Army Soldier Systems Center, Natick, Massachusetts

• Sangha Supreme Council, governs Buddhism in Thailand
• Sector skills council in the UK, a type of employers' organization for reducing skills gaps
• Sierra Student Coalition, a student-run arm of the Sierra Club, an environmental organization in the United States
• Singapore Symphony Chorus, choir of the Singapore Symphony Orchestra
• Sunday Service Choir, an American gospel group led by rapper Kanye West
• Society of the Holy Cross (Societas Sanctae Crucis), Anglo-Catholic society of male priests
• Society of Solicitors in the Supreme Courts of Scotland, a professional association of solicitors
• Species Survival Commission of the International Union for Conservation of Nature
• Statistical Society of Canada, promotes use and understanding of statistical methods

• Shaw Air Force Base, South Carolina, US (FAA code)
• Stennis Space Center, Mississippi
• Second Severn Crossing, a motorway bridge across the River Severn from England to Wales
• US Army Soldier Systems Center, Natick, Massachusetts
• Sool, Sanaag, and Cayn, three provinces in Somalia collectively known as North Eastern State since 2025
  • HBM-SSC, Militia based in SSC region
• Shetland Space Centre, a proposed spaceport in Scotland

• IBM Secure Service Container
• Shanghai Supercomputer Center, a high-performance computing service provider
• Synchronous serial communication
• Synchronous Serial Controller
• Spread-spectrum clocking, a technique used to reduce electromagnetic interference (EMI) produced by synchronous digital systems (such as computer systems)
• SQL Server Compact, a small-footprint database from Microsoft
• Supplementary service codes
• SinuSoidal Coding used for audio in MPEG-4 Part 3
• Samsung Seamless Codec used for wireless audio via Bluetooth - proprietary A2DP audio codec

• Systemic sclerosis, a form of scleroderma
• Secondary sclerosing cholangitis, a chronic cholestatic liver disease
• California species of special concern, a legal protective designation for at-risk wildlife in the state of California
• SSC buffer, a saline sodium citrate buffer commonly used in molecular biology and organic chemistry
• Stretch shortening cycle, a process of faster muscular contraction after a dynamic stretch
• Side-scattered light, a parameter of flow cytometry

• Spatial Synoptic Classification system, which is a way of diagnosing the climate of a location using air mass theory
• Sulfide stress cracking, a type of corrosion
• Super star clusters, in astronomy, possible progenitors of globular clusters
• Superconducting Super Collider, a colliding beam particle accelerator partially built in Texas by the US government before being canceled in 1993

• Thrust SSC, world's first supersonic land vehicle and current land speed record holder
• Ship-to-Shore Connector, a future air-cushion vehicle (hovercraft) of the United States Navy
• Soft structured carrier, a soft (often fabric) baby carrier
• Sistema Supporto Condotta, a kind of automated railway signalling in use on the Italian railway network
• Static synchronous compensator (STATCOM), a power electronics voltage-source converter

• Saudi Sports Company, company of a television network
• Sinhalese Sports Club Ground, a venue for international cricket matches in Colombo, Sri Lanka
• Sinhalese Sports Club, a first-class cricket club based in Colombo, Sri Lanka
• Southern States Conference, a defunct NAIA conference in the United States
• Soviet Super Cup, a defunct association football cup in the Soviet Union
• Speed Skating Canada
• Sunshine State Conference, a sports organization in Florida

• Hull classification symbol for coastal submarine
• Safe, sane and consensual, a practice in BDSM
• Scottish Submarine Centre, a naval museum in Scotland
• SkyscraperCity, an online forum for urban discussion
• Slate Star Codex, a blog about philosophy, psychiatry, and pharmacology
• South–South cooperation between developing countries
• Strawberry Shortcake
• Syrian Satellite Channel, a satellite television channel owned by RTV Syria

This disambiguation page lists articles associated with the title SSC.
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