Primarily a halfback she is a New Zealand international and has won three NRLW premierships, two with the Brisbane Broncos and one with the Sydney Roosters.
On 1 November 2020, McGregor was named in the top 3 players in the world on the official NRL site.
In late September 2022, McGregor was named as the winner of the 2022NRLWDally M Medal.[16] McGregor was also named in the NRL'S NRLW Team of the Year and in the Dream Team announced by the Rugby League Players Association. The team was selected by the players, who each cast one vote for each position.[17] McGregor also took out the RLPA's highest individual honour, the Players' Champion award.[18]
In April 2023, McGregor signed a one-year contract to return to the St George Illawarra Dragons. A few months later she was appointed as captain of the club.
Raecene signed a two-year extension with the Dragons in September 2023, keeping her with the club until the end of 2025.