In 2010, Brander began playing rugby league for the Caboolture under-18 side and the Sunshine Coast Sirens. In 2012, she joined Brisbane Women's Division 1 side, the Beerwah Bulldogs.[2] In 2014, she made her debut for Australia in their 12-8 loss to New Zealand in Wollongong.[3]
In June 2019, she again represented Queensland Country at the NRL Women's National Championships.[7] Later that month, she signed with the Brisbane Broncos.[8]
On 6 October 2019, she started at second-row in the Broncos' 30–6 Grand Final win over the Dragons and won the Karyn Murphy Medal for Player of the Match.[9]
2020
On 25 October 2020, she came off the bench in the Broncos' 20–10 Grand Final win over the Sydney Roosters.[10]