Plasma-lyte

Plasma-Lyte is a crystalloid solution for intravenous infusion, with varying electrolyte formulation depending on market. Generally the solution has a composition that mimics human physiological plasma electrolyte concentrations, osmolality and pH.[1]

It is available as a generic medication.[2][3]

Plasma-lyte 148 (pH7.4)

Plasma-Lyte 148 is a market-specific solution available in the United Kingdom and Australia, among others and has the following composition:[citation needed]

  • Sodium 140 mmol/L
  • Potassium 5 mmol/L
  • Magnesium 1.5 mmol/L
  • Chloride 98 mmol/L
  • Acetate 27 mmol/L
  • Gluconate 23 mmol/L

This solution is manufactured and marketed by Baxter International Inc.[4]

References

  1. ^ 1: Rizoli S. PlasmaLyte. J Trauma. 2011 May;70(5 Suppl):S17-8. doi: 10.1097/TA.0b013e31821a4d89. PMID 21841561.
  2. ^ "2022 First Generic Drug Approvals". U.S. Food and Drug Administration (FDA). 3 March 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.
  3. ^ "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.
  4. ^ 2: Baxter. Plasma-Lyte 148 product information. 2013. available at URL: http://www.baxterhealthcare.com.au/downloads/healthcare_professionals/cmi_pi/plasmalyte148_pi.pdf Archived 23 June 2017 at the Wayback Machine

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