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PRM1
Identifiers
Aliases	PRM1, CT94.1, P1, protamine 1
External IDs	OMIM: 182880; MGI: 97765; GeneCards: PRM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2AWR
Gene location (Human)
Chr.	Chromosome 16 (human)
End	11,281,330 bp
RNA expression pattern
	Top expressed in
	sperm; ; right testis; ; left testis; ; testicle; ; caput epididymis; ; tail of epididymis; ; right coronary artery; ; corpus epididymis; ; ectocervix; ; canal of the cervix;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding;
Cellular component	nucleosome; nucleus; nucleoplasm; chromosome;
Biological process	multicellular organism development; spermatogenesis; cell differentiation; chromosome condensation;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	5619
	19118
	ENSG00000175646
	n/a
	P04553
	P02319
	NM_002761
	NM_013637
	NP_002752
	NP_038665
	Wikidata
View/Edit Human	View/Edit Mouse

Protamine 1 is a protein that in humans is encoded by the PRM1 gene.^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175646 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Protamine 1". Retrieved 2020-03-17.

Tanaka H, Miyagawa Y, Tsujimura A, et al. (February 2003). "Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations". Molecular Human Reproduction. 9 (2): 69–73. doi:10.1093/molehr/gag010. PMID 12569175.
Tanaka H, Miyagawa Y, Tsujimura A, et al. (February 2003). "Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations". Molecular Human Reproduction. 9 (2): 69–73. doi:10.1093/molehr/gag010. PMID 12569175.
Aoki VW, Christensen GL, Atkins JF, et al. (November 2006). "Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility". Fertility and Sterility. 86 (5): 1416–22. doi:10.1016/j.fertnstert.2006.04.033. PMID 16989827.
Aoki VW, Christensen GL, Atkins JF, et al. (November 2006). "Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility". Fertility and Sterility. 86 (5): 1416–22. doi:10.1016/j.fertnstert.2006.04.033. PMID 16989827.
Aoki VW, Liu L, Jones KP, et al. (November 2006). "Sperm protamine 1/protamine 2 ratios are related to in vitro fertilization pregnancy rates and predictive of fertilization ability". Fertility and Sterility. 86 (5): 1408–15. doi:10.1016/j.fertnstert.2006.04.024. PMID 17011555.
Ravel C, Chantot-Bastaraud S, El Houate B, et al. (July 2007). "Mutations in the protamine 1 gene associated with male infertility". Molecular Human Reproduction. 13 (7): 461–4. doi:10.1093/molehr/gam031. PMID 17494104.
Depa-Martynów M, Kempisty B, Lianeri M, et al. (2007). "Association between fertilin beta, protamines 1 and 2 and spermatid-specific linker histone H1-like protein mRNA levels, fertilization ability of human spermatozoa, and quality of preimplantation embryos". Folia Histochemica et Cytobiologica. 45 (Suppl 1): S79-85. PMID 18292840.
Kempisty B, Depa-Martynow M, Lianeri M, et al. (2007). "Evaluation of protamines 1 and 2 transcript contents in spermatozoa from asthenozoospermic men". Folia Histochemica et Cytobiologica. 45 (Suppl 1): S109-13. PMID 18292846.
Hammoud S, Emery BR, Aoki VW, et al. (2007). "Identification of genetic variation in the 5' and 3' non-coding regions of the protamine genes in patients with protamine deregulation". Archives of Andrology. 53 (5): 267–74. doi:10.1080/01485010701569890. PMID 18309899. S2CID 1012898.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175646 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: Protamine 1". Retrieved 2020-03-17.

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PRM1

References

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