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PMC may refer to:

Computing

Pacific Microelectronics Centre, acquired by Sierra Semiconductor in 1994 to form PMC-Sierra
Parallel model combination, a hidden Markov model-based method for speech recognition
PCI Mezzanine Card, a form factor for computer circuit boards
Polymorphic containers, a feature of the Parrot virtual machine
Portable Media Center, a hard drive-based portable media player
Programmable metallization cell, new memory technology that uses copper nanowires

Paramyotonia congenita, a genetic disorder
Percent modern carbon (pMC), a relative unit used for the calculation of radiocarbon dates
PhysMath Central, a defunct journal imprint
Polar mesospheric clouds, also known as noctilucent clouds, a weather phenomenon
Pontine micturition center, part of the brainstem
Posteromedial cortex, the rear (posterior) portion of the centerline (medial) face of the cerebral cortex
Premotor cortex, part of the cerebral cortex
Pseudomembranous colitis, a disease of the colon
PubMed Central, a collection of journal articles

Politico-media complex, a name given to the network of relationships between a state's political classes and its media industry
Professional–managerial class, a social class within capitalism.

Pakistan Medical Commission, a statutory regulatory authority for medical and dental practitioners
Pan-Mass Challenge, a charity bike-a-thon
Permanent Mandates Commission, a commission of the League of Nations
Philippine Marine Corps, part of the Philippine Navy
Polymer matrix composite, a composite material
Population Media Center, an organization headquartered in Vermont, United States
Precious Metal Clay, a brand of metal clay
Presidential Memorial Certificate, United States
Pressed Metal Corporation, an Australian automotive manufacturer
Private Medical Conference of an astronaut of the ISS in flight with a doctor on the ground
Project management committee
Punjab & Maharashtra Co-operative Bank
Pyeonghwa Motors Corp., a car manufacturer in North Korea
Pearl Milling Company, a brand commonly known for pancake/waffle mix and maple syrup