DOKUMEN123.COM

encodes a cell cycle inhibitor that binds to G1 cyclin-CDK complexes. Thus p57KIP2 causes arrest of the cell cycle in G1 phase. CDKN1C was found to lead to...

The CIP/KIP family is made up of three proteins: p21cip1/waf1, P27kip1, p57kip2 These proteins share sequence homology at the N-terminal domain which allows...

homozygously deleted. The genes h19, insulin-like growth factor II (IGF-II), and p57kip2 are important for fetal growth and development. They are located on chromosome...

that inhibit cell cycle progression at G1, such as p21CipP1, p27Kip1, and p57Kip2. Furthermore, regulators of Cdk4 and Cdk6 activity, such as members of...

Der Kaloustian VM, Higgins MJ (November 2003). "Silencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith-Wiedemann syndrome"...

Shimano H, Gotoda T, Nishimori S, Tanaka K, Yamada N (December 2003). "p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the...

cyclin D (Cánepa et al., 2007). The Cip/Kip families (p21Cip1, p27Kip1, and p57Kip2) also bind to cyclin/CDK complexes and prohibit advancement through the...

"Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen". Proceedings of...

interstitium while p57Kip2 encodes a cyclin-dependent kinase inhibitor which is linked to Beckwith-Wiedemann syndrome. Pod1, p57Kip2 and integrin α3 (ITGA3)...

inhibit the tumor suppressor pathways p14ARF/p53/p21WAF1/CIP1, p16INK4a/pRb, p57KIP2, PTEN, E-cadherin and activating the angiogenesis-associated genes FGF2...

homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissues". Hum Mol Genet...

(October 2006). "CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene". The Journal of Biological Chemistry...

and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2". EMBO Rep. 9 (4): 377–83. doi:10.1038/embor.2008.7. PMC 2288761. PMID 18274550...

"Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen". Proceedings of...

other members of the "Cip/Kip" family which include the p21Cip1/Waf1 and p57Kip2 genes. In addition to this structural similarity the "Cip/Kip" proteins...

Morisaki T, Mukai T (August 1998). "A novel gene, ITM, located between p57KIP2 and IPL, is imprinted in mice". DNA Research. 5 (4): 235–40. CiteSeerX 10...

lymphatic ECs (LECs). For example, specific mRNAs such as VEGFR-3 and p57Kip2 were expressed by the BEC that was induced to express Prox-1. Lymphatic-specific...

PAK4-dependent signals also modulate the expression of genomic targets, including p57Kip2. The PAK4 activity and expression has been shown to be inhibited by chemical...