NCAPG

NCAPG
Identifiers
AliasesNCAPG, CAPG, CHCG, NY-MEL-3, YCG1, non-SMC condensin I complex subunit G
External IDsOMIM: 606280; MGI: 1930197; HomoloGene: 44071; GeneCards: NCAPG; OMA:NCAPG - orthologs
Orthologs
SpeciesHumanMouse
Entrez

64151

54392

Ensembl

ENSG00000109805

ENSMUSG00000015880

UniProt

Q9BPX3

E9PWG6

RefSeq (mRNA)

NM_022346

NM_019438

RefSeq (protein)

NP_071741

NP_062311

Location (UCSC)Chr 4: 17.81 – 17.84 MbChr 5: 45.83 – 45.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene.[5][6][7] CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

Interactions

NCAPG has been shown to interact with DNMT3B.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000109805 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015880 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jäger D, Stockert E, Jäger E, Güre AO, Scanlan MJ, Knuth A, Old LJ, Chen YT (Aug 2000). "Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library". Cancer Res. 60 (13): 3584–91. PMID 10910072.
  6. ^ Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts". J. Biol. Chem. 276 (8): 5417–20. doi:10.1074/jbc.C000873200. PMID 11136719.
  7. ^ "Entrez Gene: NCAPG non-SMC condensin I complex, subunit G".
  8. ^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359.

Further reading


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