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A lymphoblast is a modified naive lymphocyte with altered cell morphology. It occurs when the lymphocyte is activated by an antigen and increased in volume...

so proteins encoded by the human genome, only 6,000 are detected in lymphoblastoid cells. The most abundant protein in nature is thought to be RuBisCO...

Human Lymphoblastoid EBV-transformed B cell ECACC Cellosaurus K562 Human Lymphoblastoid CML blast crisis ECACC Cellosaurus KBM-7 Human Lymphoblastoid CML...

eunuchs lived on average 14 to 19 years longer than uncastrated men. Lymphoblastoid cell lines established from blood samples of centenarians have significantly...

dendritic cells, macrophages, neutrophils, helper T cells and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 belongs to...

plasma cell leukemia unknown Epstein-Barr virus-transfected B cell lymphoblastoid CVCL_1072 AV3 Virtual amnion HeLa cervical adenocarcinoma CVCL_1904...

genetic variants these explain only a small fraction of the heritability. Lymphoblastoid cell lines established from blood samples of centenarians have significantly...

body for the individual's lifetime. When EBV infects B cells in vitro, lymphoblastoid cell lines eventually emerge that are capable of indefinite growth....

McCoy′s 5A medium (or RPMI 1630), it was originally formulated to support lymphoblastoid cells in suspension cultures, but can also support a wide variety of...

prolactin and tumor necrosis factor-beta genes on human chromosome 6p using lymphoblastoid cell deletion mutants". Somatic Cell and Molecular Genetics. 15 (3):...

Selicorni A, Barco A, Larizza L (2012). "Histone acetylation deficits in lymphoblastoid cell lines from patients with Rubinstein–Taybi syndrome". Journal of...

The JY cell line is an Epstein–Barr virus (EBV)-immortalised B cell lymphoblastoid line. JY cells express HLA class-I A2 and class-II DR. JY is a suspension...

account, in part, for the higher PARP activity in humans than rats. Lymphoblastoid cell lines established from blood samples of humans who were centenarians...

(November 2002). "Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug...

Human Genome Diversity Cell Line Panel is a resource of 1,063 cultured lymphoblastoid cell lines (LCLs) from 1,050 individuals in 52 world populations, banked...

filter after the exposure on adult human liver stem cells and human lymphoblastoid cells". Science of the Total Environment. 593–594: 18–26. Bibcode:2017ScTEn...

cancer cells. Altered expression of miR-618 has been seen in the human lymphoblastoid TK6 cell line, with downregulation following stress-related stimulated...

is expressed. The cells grow in a suspension, are diploid, and are lymphoblastoid in morphology. B Fadeel (30 September 2004). "Raji revisited: cytogenetics...

cytokinesis-block micronucleus cytome assay and aneuploidy in human B lymphoblastoid cell lines". Mutagenesis. 26 (3): 421–9. doi:10.1093/mutage/geq110....

ribosyl)ation capability measured in mononuclear cells. Furthermore, lymphoblastoid cell lines from peripheral blood lymphocytes of humans over age 100...

elephant and man) correlates with maximum lifespan of the species. Lymphoblastoid cell lines established from blood samples of humans who were centenarians...

enzymatic activity has been assessed in Epstein-Barr virus-immortalized lymphoblastoid cell lines (a B lymphocyte that divides continuously due to Epstein-Barr...

Company. JY cell line, Epstein-Barr virus (EBV)-immortalised b cell lymphoblastoid line This disambiguation page lists articles associated with the title...

is confirmed by enzyme activity testing in lymphocytes, immortalized lymphoblastoid cells, or fibroblasts, as well as HMGCL gene mutation studies. There...

(February 1980). "Amino terminal sequence of the major component of human lymphoblastoid interferon". Science. 207 (4430): 527–528. Bibcode:1980Sci...207..527Z...

transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia". Proceedings of the National Academy of Sciences of the United...

filter after the exposure on adult human liver stem cells and human lymphoblastoid cells". Science of the Total Environment. 593–594: 18–26. Bibcode:2017ScTEn...

"Ectopic transcription of the parathyroid hormone gene in lymphocytes, lymphoblastoid cells and tumour tissue". The Journal of Endocrinology. 135 (2): 249–256...

transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia". Proceedings of the National Academy of Sciences of the United...

HLA-DR4, HLA-DR7, and HLA-DR8 were purified from homozygous human B lymphoblastoid cell lines and crystals were grown for diffraction studies. Strominger...

show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci". Molecular Autism. 3 (1):...

Lapin BA, Agrba VZ, Yakovleva LA, Samilchuk EI (1976). "Continuous lymphoblastoid suspension cultures from cells of haematopoietic organs of baboons with...

Borland VCL Lower control limit, a statistical process control term Lymphoblastoid cell line, the outcome of lymphocyte infection by Epstein–Barr virus...

the Branched-Chain Alpha-Keto Acid Decarboxylase (E1) Component in Lymphoblastoid Cells Derived from Patients with Maple Syrup Urine Disease". J Clin...

of taurine, zinc and tocopherol on retinol-induced damage in human lymphoblastoid cells". The Journal of Nutrition. 114 (12): 2256–2261. doi:10.1093/jn/114...

genetically determined DNA repair capability appears to influence lifespan. Lymphoblastoid cell lines established from blood samples of humans who lived past 100...

1971, a viral agent with FV-like characteristics was isolated from lymphoblastoid cells released from a human nasopharyngeal carcinoma (NPC) from a Kenyan...

1988). "Macrophage colony-stimulating factor is produced by human T lymphoblastoid cell line, CEM-ON: identification by amino-terminal amino acid sequence...

oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells". Chemical Research in Toxicology. 19 (3): 399–406. doi:10.1021/tx050283e...

Differential and cell-type specific usage of upstream exon sequences in B-lymphoblastoid cells". J. Biol. Chem. 268 (6): 4355–61. doi:10.1016/S0021-9258(18)53617-6...

ribosyl)ation capability measured in mononuclear cells. Furthermore, lymphoblastoid cell lines from peripheral blood lymphocytes of humans over age 100...

next to an enhancer called LOC130068517, also known as ATAC-STARR-Seq Lymphoblastoid Active Region 29826. Expression is ubiquitous and high across may tissues...

Strnad BC, Nonoyama M, Nelson-Rees WA (1979). "Establishment of a lymphoblastoid cell line and isolation of an Epstein-Barr-related virus of gorilla...

exon. These messages are expressed in Epstein-Barr Virus transformed lymphoblastoid cell cultures. The ratio of these messages varies widely and unpredictably...

following the isolation of IL-12 from Epstein-Barr virus-transformed B-lymphoblastoid cells. Shortly following the discovery of IL-12, a protein known as...

greater among individuals who were both frail and living in poverty. Lymphoblastoid cell lines established from blood samples of humans who lived past 100...

by DNA fragmentation induced in main nuclei and micronuclei of human lymphoblastoid cells treated with colcemid". Mutation Research. 762: 10–6. Bibcode:2014MRFMM...

Severino, L. (2013). In vitro study of AFB1 and AFM1 effects on human lymphoblastoid Jurkat T-cell model. J. Immunotoxicol., 11, 353–358. Marchese, S.; Polo...

micronuclei in hamster cells of the V79 cell line as well as human lymphoblastoid cells in a dose-dependent manner. Exposure to coumestrol also causes...

inserted into the thymidine kinase gene in a chromosome within human lymphoblastoid cells in culture. They inserted 8-oxo-dG into about 800 cells, and could...

D., MPH, NAMED DIRECTOR OF CBER". Retrieved March 13, 2014. "Human Lymphoblastoid Interferon" (PDF). J Bio Chem. "The Nobel Prize in Chemistry 1972"....

Motykiewicz, G.; Santella, R. M. (2005-01-19). "DNA Repair Capacity of Lymphoblastoid Cell Lines From Sisters Discordant for Breast Cancer". JNCI Journal...

of the fumarate hydratase activity in cultured skin fibroblasts or lymphoblastoid cells and demonstrating reduced activity (≤60%) or by molecular genetic...

STAT1 GM12878 (human lymphoblastoid) Promoter TAF1 GM12878 (human lymphoblastoid) Promoter TRIM22 GM12878 (human lymphoblastoid) Promoter REST H1-hESC...

Warren ST, Geschwind DH (2007). "Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared...

phosphatidylinositol hydrolysis pathway in HIV-infected lymphocytes and lymphoblastoid cells is due to inhibition of the inositol 1,4,5-trisphosphate 1,3,4...

encoded from the gene HLA-F was originally isolated from the human lymphoblastoid cell line 721. The HLA-F gene is located on the short arm of chromosome...

Fanconi anaemia, ataxia telangiectasia fibroblast and Bloom's syndrome lymphoblastoid cell lines as detected by conventional cytogenetic analysis and fluorescence...

Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant...

activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia". Proceedings of the National Academy of Sciences of the United...

complexes isolated with TAP1 antibodies from digitonin lysates of human B lymphoblastoid cells. Tapasin binds HC/β2m along with ER chaperones to the peptide...

PMID 6933565. Fujii H, Chen SH, Akatsuka J, et al. (1981). "Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". European Journal of Immunology. 27 (11): 2805–11. doi:10...

Londin ER, Rigoutsos I (2014), "IsomiR Expression Profiles in Human Lymphoblastoid Cell Lines Exhibit Population and Gender Dependencies.", Oncotarget...

envelope glycoprotein gp 120 of human immunodeficiency virus 1 from the lymphoblastoid cell line H9. Presence of complex-type oligosaccharides with bisecting...

Senie RT, Motykiewicz G, Santella RM (2005). "DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer". J. Natl. Cancer...

type 1 (HIV-1)-specific cytotoxic T-lymphocyte responses utilizing B-lymphoblastoid cell lines transduced with the CD4 gene and infected with HIV-1". Journal...

epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells". Drug Metab. Dispos. 27 (7): 798–803. doi:10.1016/S0090-9556(24)15228-2...

The human homolog was isolated in 1980 as a 25kDa protein (p25) of T-lymphoblastoid cell line MOLT-3 binding with anti-monkey-thymocyte antisera. The discovery...

characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells". Proceedings of the National Academy of Sciences of the United...

M, Washizuka S, et al. (2004). "Expression of HSPF1 and LIM in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia"...

taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study". BMC Cancer. 12:...

Shein, R.; Karayiannis, P.; McDonald, J. A.; Thomas, H. C. (1985). "Lymphoblastoid interferon therapy of chronic hepatitis B virus infection". Hepatology...

been shown to be associated with changes in cytokine expression using lymphoblastoid cells of heterozygous carriers vs homozygous wild type individuals Specifically...

29% of NSCLC had epigenetic reduction of MSH2 expression. In acute lymphoblastoid leukemia (ALL), no MSH2 mutations were found while 43% of ALL patients...

Bassell, Gary J. (9 May 2012). "Excess protein synthesis in FXS patient lymphoblastoid cells can be rescued with a p110β-selective inhibitor". Molecular Medicine...

human peripheral blood mononuclear cells (PMBCs) and regulation of B-lymphoblastoid cell proliferation by GnRH-I and GnRH-II". Exp. Clin. Endocrinol. Diabetes...

they successfully constructed a human NotI jumping library from a lymphoblastoid cell line and a human chromosome 3-specific NotI jumping library from...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". Eur. J. Immunol. 27 (11): 2805–11. doi:10.1002/eji.1830271110...

inhibit progression beyond G1 phase in some human cells, including lymphoblastoid cells. Its proposed mechanism of action is an iron/zinc chelator that...

monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines". J. Immunol. 129 (2): 623–8. doi:10.4049/jimmunol.129.2...

Pfeifer GP, Hu VW (August 2010). "Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders...

"Purification and characterization of multiple components of human lymphoblastoid interferon-alpha". J. Biol. Chem. 267 (21): 15210–6. doi:10.1016/S0021-9258(18)42167-9...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". Eur. J. Immunol. 27 (11): 2805–11. doi:10.1002/eji.1830271110...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". Eur. J. Immunol. 27 (11): 2805–11. doi:10.1002/eji.1830271110...

nonpolymorphic MHC class II isotype, HLA-DQA2, is expressed on the surface of B lymphoblastoid cells". Journal of Immunology. 158 (5): 2116–2125. doi:10.4049/jimmunol...

phosphatidylinositol hydrolysis pathway in HIV-infected lymphocytes and lymphoblastoid cells is due to inhibition of the inositol 1,4,5-trisphosphate 1,3,4...

a new DNA polymerase in human cancer cells. His team later studied lymphoblastoid interferon in humans and explored lipid-soluble antifolates to address...

been a pioneer in the use of ex vivo cell lines, such as immortalized lymphoblastoid cell lines, to discover novel gene associations with activity of anticancer...

FAM50B. Along with this, PXDC1 had a 2:1 paternal expression bias in lymphoblastoid cell lines and whole blood. GRCh38: Ensembl release 89: ENSG00000168994...

a new variant of human interferon alpha identified in virus induced lymphoblastoid cells". Dev. Biol. Stand. 60: 111–22. PMID 2995168. Henco K, Brosius...

Newton, K.A.; Westbury, G. (15 January 1983). "Evaluation of human lymphoblastoid interferon in advanced malignant melanoma". Cancer. 51 (2): 273–6. doi:10...

phosphorylation and activation of CREB transcription factor in both Jurkat lymphoblastoid T cells and primary peripheral blood mononuclear cells". J. Immunol...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". European Journal of Immunology. 27 (11): 2805–11. doi:10...

U, Cullen BR (2012). "The viral and cellular microRNA targetome in lymphoblastoid cell lines". PLOS Pathogens. 8 (1) e1002484. doi:10.1371/journal.ppat...

"Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African...

bladder, and the eye. KIAA0895L has been shown to be up regulated in lymphoblastoid cells from males with autism that is caused by an expansion of a CGG...

particular, the 297-residue isoform of this enzyme is highly expressed in lymphoblastoid cells. The loss of NT5C3 in pyrimidine 5' nucleotidase deficiency, an...

"Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes". Journal of Experimental Medicine...

oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells". Chemical Research in Toxicology. 19 (3): 399–406. doi:10.1021/tx050283e...

"Identification of Quantitative Trait Loci Underlying Proteome Variation in Human Lymphoblastoid Cells". Molecular & Cellular Proteomics. 9 (7): 1383–1399. doi:10.1074/mcp...

inserted into the thymidine kinase gene in a chromosome within human lymphoblastoid cells in culture. They inserted 8-oxo-dG into about 800 cells, and could...

Geschwind, Daniel H. (2007-07-15). "Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". European Journal of Immunology. 27 (11): 2805–2811. doi:10...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". Eur. J. Immunol. 27 (11): 2805–2811. doi:10.1002/eji...

protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells". Eur. J. Immunol. 27 (11): 2805–11. doi:10.1002/eji.1830271110...

"Use of RAPD to detect sodium arsenite-induced DNA damage in human lymphoblastoid cells". Toxicology. 239 (1–2): 108–15. doi:10.1016/j.tox.2007.06.101...

reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines". PLOS ONE. 4 (6) e5878. Bibcode:2009PLoSO...4.5878W. doi:10...

"MicroRNA signatures associated with immortalization of EBV-transformed lymphoblastoid cell lines and their clinical traits". Cell Proliferation. 44 (1): 59–66...