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ISG15-peptide fusions and also removes ISG15 (deISGylation) from native conjugates. The effects of ISGylation are incompletely understood and involve both...

ubiquitin-related modifier) neddylation, the covalent linkage to the Nedd protein ISGylation, the covalent linkage to the ISG15 protein (interferon-stimulated gene...

conjugates from a broad range of protein substrates, a process known as deISGylation. The USP18 gene consists of 11 exons that encode a 43 kDa protein. The...

and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on...

which includes other reactions such as ubiquitination, SUMOylation, and ISGylation. Neddylation has been reported for both histone and non-histone protein...

evolutionary repurposing of viral proteases for deubiquitination and deISGylation as mechanism for influencing the host innate immune system response is...

Chen*, and Chen Wang. Herc5 Attenuates Influenza A Virus by Catalyzing ISGylation of Viral NS1 Protein. Journal of Immunology, 2010, 184, 5777-5790 6. Bo...

"Interferon-Inducible Ubiquitin E2, Ubc8, Is a Conjugating Enzyme for Protein ISGylation". Mol. Cell. Biol. 24 (21): 9592–600. doi:10.1128/MCB.24.21.9592-9600...

DE (2007). "Negative Regulation of ISG15 E3 ligase EFP through its autoISGylation". Biochem. Biophys. Res. Commun. 354 (1): 321–7. Bibcode:2007BBRC..354...