Search Results: Homodimeric

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Protein dimer
Senin, 2026-03-02 11:38:50

exception is dimers that are linked by disulfide bridges such as the homodimeric protein NEMO. Some proteins contain specialized domains to ensure dimerization...

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Racemic crystallography
Selasa, 2025-11-04 12:38:39

Racemic crystal structure of homodimeric Rv1738 from Mycobacterium tuberculosis...

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Two-component regulatory system
Sabtu, 2025-10-04 03:27:18

regulator (RR) by a histidine kinase (HK). Histidine kinases are typically homodimeric transmembrane proteins containing a histidine phosphotransfer domain...

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King cobra
Sabtu, 2026-05-16 07:39:00

R. M. (2010). "Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)"...

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Anoxygenic photosynthesis
Rabu, 2025-12-10 05:51:23

Sen-Fang; Qin, Xiaochun (2022-12-14). "Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c". Nature Communications. 13 (1):...

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Alkaline phosphatase
Jumat, 2026-05-15 12:31:37

hemoglobinuria and acute myelogenous leukaemia. Alkaline phosphatase is homodimeric enzyme, meaning it is formed with two molecules. Three metal ions, two...

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Rop protein
Jumat, 2023-08-18 14:38:21

preprimer RNA, RNA II, and its antisense RNA, RNA I. Structurally, Rop is a homodimeric four-helix bundle protein formed by the antiparallel interaction of two...

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Polyketide synthase
Senin, 2026-05-18 22:18:48

or dissociable molecular assemblies; type III PKSs exist as smaller homodimeric proteins. PKSs can be classified into three types: Type I PKSs Large...

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TGF beta receptor
Minggu, 2025-10-19 03:00:52

low affinity for TGFβ2. TGFβR3 (β-glycan) has a high affinity for both homodimeric TGFβ1 and TGFβ2 and in addition the heterodimer TGF-β1.2. The TGFβ receptors...

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Fluorine
Jumat, 2026-05-29 05:30:52

Schlöder, T.; Riedel, S. (2012). "Investigation of Heterodimeric and Homodimeric Radical Cations of the Series: [F2O2]+, [F2Cl2]+, [Cl2O2]+, [F4]+, and...

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UDP-glucose 4-epimerase
Jumat, 2025-09-26 20:19:42

(EC 5.1.3.2), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This...

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Enterococcus faecalis
Minggu, 2026-05-10 02:20:38

used to show detailed insights into the unfolding of the E. faecalis homodimeric repressor protein CylR2. The E. faecalis genome consists of 3.22 million...

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Lysibody
Jumat, 2026-03-20 21:58:02

held together by hinge-region disulfide bonds. Thus, lysibodies are homodimeric hybrid immunoglobulin G molecules that can bind with high affinity and...

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Microprotein
Senin, 2026-05-25 05:11:46

post-translational regulators. Microproteins disrupt the formation of heterodimeric, homodimeric, or multimeric complexes. Furthermore, microproteins can interact with...

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Sex hormone–binding globulin
Rabu, 2026-05-13 17:36:47

site and turns off production of SHBG. Sex hormone-binding globulin is homodimeric, meaning it has two identical peptide chains making up its structure...

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Intracellular antibody-mediated degradation
Jumat, 2021-09-03 21:51:44

structure of two molecules of the C-terminal PRYSPRY domain of TRIM21 (top right and top left) complexed with homodimeric Ig gamma-1 chain C region (center)....

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Restriction enzyme
Senin, 2026-04-27 15:31:26

Type II site-specific deoxyribonuclease-like Structure of the homodimeric restriction enzyme EcoRI (cyan and green cartoon diagram) bound to double stranded...

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Uteroglobin
Minggu, 2026-04-19 01:02:59

dimeric proteins found only in mammals. This antiparallel disulfide linked homodimeric protein is multifunctional and found in various tissues in various names...

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Phenylalanine hydroxylase
Rabu, 2025-07-30 18:07:21

whereas eukaryotic PAH exists in an equilibrium between homotetrameric and homodimeric forms. The dimerization interface is composed of symmetry-related loops...

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OXCT1
Kamis, 2025-07-17 01:12:31

the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic...

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Iron superoxide dismutase
Jumat, 2025-07-04 19:38:46

connecting the β1 and β2 strands within the enzyme. FeSOD can also exist in homodimeric or homotetrameric forms, depending on the organism. Like its structural...

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Shugoshin N terminal protein domain
Kamis, 2024-02-22 04:30:23

Shugoshin protein is a coiled-coil which can be further described as a homodimeric parallel coiled-coil. Kitajima TS, Kawashima SA, Watanabe Y (February...

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Spätzle (protein)
Kamis, 2025-10-23 15:23:41

the final spz[221-326] (Spaetzle C-106) part as the mature protein. Homodimeric spz binds to a dimeric toll receptor in fruit flies and related organisms...

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Glur2 RNA editing
Sabtu, 2026-01-24 12:01:20

combine to form tetramers. They are usually heterotrimeric but can be homodimeric. Each AMPAR has four sites to which an agonist (such as L-glutamate)...

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KIF17
Sabtu, 2025-07-19 13:16:23

kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors...

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FYVE domain
Jumat, 2025-09-19 23:45:11

Sudharshan E, et al. (November 2001). "Multivalent endosome targeting by homodimeric EEA1". Mol. Cell. 8 (5): 947–58. doi:10.1016/S1097-2765(01)00385-9. PMID 11741531...

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PYGL
Selasa, 2026-06-02 12:38:53

humans is encoded by the PYGL gene on chromosome 14. This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to...

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ZHX2
Rabu, 2025-07-16 05:29:21

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear...

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ZP3
Senin, 2026-03-30 22:45:30

with the ZP-N domain of a second molecule to generate an antiparallel homodimeric arrangement required for protein secretion. The Zona Pellucida (ZP) is...

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GOT2
Senin, 2026-01-26 09:41:17

a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation...

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CNDP1
Kamis, 2025-12-18 19:07:29

family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains...

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Glutathione synthetase
Minggu, 2025-07-20 15:05:39

symptoms in plants and human beings alike. In eukaryotes, this is a homodimeric enzyme. The substrate-binding domain has a three-layer alpha/beta/alpha...

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Amar Nath Bhaduri
Jumat, 2026-02-06 05:26:01

chemical biologist, known for his studies on UDP-glucose 4-epimerase, a homodimeric epimerase found in cells and his work on Leishmania donovani, the protozoal...

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Aspartate racemase
Minggu, 2025-09-28 10:07:31

This protein shares nearly identical enzymological properties with homodimeric aspartate racemase isolated from Streptococcus thermophilus, but has...

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HAMP domain
Jumat, 2024-10-04 17:16:22

domains and thus regulates the phosphorylation or methylation activity of homodimeric receptors. Aravind L, Ponting CP (July 1999). "The cytoplasmic helical...

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Immunoglobulin light chain
Kamis, 2026-03-05 09:53:12

as part of their adaptive immune systems, a functional heavy-chain homodimeric antibody-like molecule referred to as IgNAR (immunoglobulin new antigen...

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Lanthanide-dependent methanol dehydrogenase
Minggu, 2026-05-10 11:23:48

AHDs revealed more about the biological activity of lanthanides. In the homodimeric Ce3+-dependent methanol dehydrogenase sampled from methylacidiphilum...

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Α-Galactosidase
Jumat, 2026-06-05 00:10:40

internal insertion region to form its dimer interface. This enzyme is a homodimeric glycoprotein that hydrolyses the terminal α-galactosyl moieties from...

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Meganuclease
Selasa, 2026-05-19 23:34:44

have developed a collection of over 20,000 protein domains from the homodimeric meganuclease I-CreI as well as from other meganucleases scaffolds. They...

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STC2
Sabtu, 2025-07-19 14:23:33

in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have...

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Glycerol kinase
Senin, 2022-05-09 02:47:39

there were 20 structures of this protein in the PDB, most of which are homodimeric. Glycerol Kinase Glycerol+Kinase at the U.S. National Library of Medicine...

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ABCD4
Rabu, 2025-07-16 04:20:18

which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane...

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Peridinin-chlorophyll-protein complex
Jumat, 2022-02-25 18:22:36

forms, a homodimeric form composed of two 15-kD monomers, and a monomeric form of around 32kD believed to have evolved from the homodimeric form via gene...

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ABCD1
Kamis, 2025-07-31 20:30:43

which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely...

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Carbon monoxide dehydrogenase
Senin, 2026-03-23 04:31:31

their phylogenetic relationship Homodimeric Ni,Fe-CODHs contain five-metal clusters. They exist either in a homodimeric form (also called monofunctional)...

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GOT1
Senin, 2026-01-26 09:38:30

metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Click on genes, proteins and metabolites below...

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Ribonuclease III
Rabu, 2026-04-08 23:13:51

domain structure. Class 1 RNase III Class 1 RNase III enzymes have a homodimeric structure whose function is to cleave dsRNA into multiple subunits. It...

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Non-homologous end joining
Minggu, 2026-01-04 17:21:50

dormant cells. The archaeal NHEJ system in Methanocella paludicola have a homodimeric Ku, but the three functions of LigD are broken up into three single-domain...

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Anion exchanger family
Sabtu, 2026-04-18 04:35:16

22992757; 29% identity in 90 residues). Animal AE proteins consist of homodimeric complexes of integral membrane proteins that vary in size from about...

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Lymphangioleiomyomatosis
Senin, 2026-05-25 13:40:48

of chylous effusions and lymphatic involvement). VEGF-D is a secreted homodimeric glycoprotein and a member of the VEGF family of growth factors, is known...

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Influenza non-structural protein
Jumat, 2020-09-11 19:46:25

Influenza non-structural protein (NS1) is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds...

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ZHX1
Jumat, 2025-07-18 01:53:28

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear...

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Nitrate reductase
Minggu, 2026-05-10 23:21:05

weissflogii. The nitrate reductase of higher plants, algae, and fungi is a homodimeric cytosolic protein with five conserved domains in each monomer: 1) an...

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Nucleoid
Kamis, 2026-06-04 08:18:53

structuring protein (H-NS) from other NAPs is the ability to switch from the homodimeric form at relatively low concentrations (<1 × 10−5 M) to an oligomeric...

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Shelterin
Sabtu, 2024-09-21 05:04:01

than TPP1 and POT1. TRF1 (Telomere Repeat binding Factor 1): TRF1 is a homodimeric protein that binds to the double-stranded TTAGGG region of the telomere...

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Trefoil knot fold
Senin, 2024-07-15 13:27:56

E. (2006). "Probing Nature's Knots: The Folding Pathway of a Knotted Homodimeric Protein". Journal of Molecular Biology. 359 (5): 1420–1436. doi:10.1016/j...

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CooA
Senin, 2025-12-22 11:58:21

N-terminal amine as ligands in both ferric and ferrous states. CooA is a homodimeric, heme-containing transcription factor of the CAP/CRP family, with each...

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Nitrogenase
Sabtu, 2026-03-07 16:34:36

ambient temperatures. A usual assembly consists of two components: The homodimeric Fe-only protein, the reductase which has a high reducing power and is...

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Geranyltranstransferase
Sabtu, 2023-08-26 21:11:44

geranyltranstransferase, is well characterized. FPPS is a ~30 kDa Mg2+ dependent homodimeric enzyme that synthesizes (E, E)-farnesyl pyrophosphate in a successive...

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BCR (gene)
Kamis, 2025-07-17 22:47:42

of the BCR-ABL oncoprotein (BCR30-65) resulted in a new pH-sensitive homodimeric antiparallel coiled coil. Although the BCR-ABL fusion protein has been...

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Leucine zipper
Rabu, 2026-05-06 00:27:58

higher evolution complexity. Heterodimeric bZIP proteins differ from homodimeric bZIP and from each other in protein-protein interaction affinity. These...

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CD135
Rabu, 2025-08-06 19:03:39

ternary complex is formed in which two FLT3 molecules are bridged by one (homodimeric) FLT3L. The formation of such complex brings the two intracellular domains...

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ANO1
Minggu, 2025-09-28 14:32:07

Markwardt F, Schmalzing G (February 2011). "TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels". Molecular & Cellular Proteomics...

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Endoglin
Minggu, 2025-10-12 05:31:15

ligand via interaction of two copies of OR1 with the knuckle regions of homodimeric BMP-9. In addition to rationalizing a large number of HHT1 mutations...

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3-dehydroquinate dehydratase
Jumat, 2025-07-18 01:04:46

enzyme is from Escherichia coli (gene aroD) and related bacteria. It is a homodimeric protein. In fungi, dehydroquinase forms the core of the pentafunctional...

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BMPR2
Jumat, 2025-08-08 17:50:35

oligomers increase, suggesting that the equilibrium shifts towards the homodimeric form. The low affinity for ligands suggests that BMPR2 may differ from...

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S100A6
Sabtu, 2025-07-19 14:13:01

NMR, 20 STRUCTURES 1cnp: THE STRUCTURE OF CALCYCLIN REVEALS A NOVEL HOMODIMERIC FOLD FOR S100 CA2+-BINDING PROTEINS, NMR, 22 STRUCTURES 1jwd: Ca2+-induced...

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Glutathione S-transferase, C-terminal domain
Jumat, 2025-10-17 20:23:20

also form heterodimers of the A1 and A2 or YC1 and YC2 subunits. The homodimeric enzymes display a conserved structural fold. Each monomer is composed...

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Platelet-derived growth factor receptor
Rabu, 2025-11-26 11:55:40

"Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes". Kidney International. 41 (3): 571–4. doi:10.1038/ki...

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CKMT1A
Selasa, 2025-10-21 03:52:14

CKMT1A is located in the mitochondrial intermembrane space and form both homodimeric and homooctameric molecules that are readily interconvertible. Like all...

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Cobratoxin
Jumat, 2026-01-30 08:36:53

form and a disulfide-bound dimeric form. α-Cobratoxin dimers can be homodimeric as well as heterodimeric with cytotoxin 1, cytotoxin 2 and cytotoxin...

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Choline kinase
Rabu, 2025-10-01 09:47:33

encoded by two separate genes, CHKA and CHKB and are only active in their homodimeric, heterodimeric and oligomeric forms. As of late 2007, six structures...

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Bone growth factor
Rabu, 2025-07-16 23:42:17

polypeptide chains A and B. The combination of these polypeptides form the homodimeric (AA) or (BB), or heterodimeric (AB) chains of PDGF. Fibroblast growth...

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Metastatic breast cancer
Jumat, 2026-06-05 01:52:48

in cartilaginous tissues. Endoglin is a cell-surface disulfide-linked homodimeric glycoprotein which binds to integrins and other RGD ligands and is a...

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S100 protein
Sabtu, 2025-10-04 15:18:15

THP-1 cells. Most S100 proteins consist of two identical polypeptides (homodimeric), which are held together by noncovalent bonds. They are structurally...

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ProtCID
Selasa, 2025-10-28 08:52:58

structures of homologous proteins. Its main goal is to identify and cluster homodimeric and heterodimeric interfaces observed in multiple crystal forms of homologous...

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Galectin-7
Kamis, 2026-05-21 01:58:45

Reitzenstein C, Versluis K, Kaltner H, Pieters RJ, et al. (September 2003). "Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human...

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KIF3B
Senin, 2026-01-19 12:32:12

part of the Kinesin-2 family of kinesins that form heterotrimeric or homodimeric complexes. Expression of the three motor subunits of heterotrimeric kinesin-2...

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ABCD2
Sabtu, 2025-07-19 11:58:53

which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane...

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Interferon-gamma receptor
Selasa, 2025-10-21 19:38:55

Tyrosine-phosphorylated Stat1 molecules dissociate from their receptor tether and form homodimeric complexes. Activated Stat1 translocates to the nucleus and, after binding...

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Interferon gamma receptor (IFNGR1) family
Kamis, 2025-02-27 16:28:30

homodimers, whereas the cellular IFN-gammaR dimerises only upon binding the homodimeric IFN-gamma. The existence of the virus protein as a dimer in the absence...

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PLOD3
Rabu, 2025-07-16 05:10:20

the PLOD3 gene. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum...

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ABCD3
Sabtu, 2025-07-19 23:08:43

which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely...

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Peptidomimetic
Senin, 2026-06-01 10:12:44

cooperativity results from the molecule's ability to also mimic the homodimeric structure of Smac, which is functionally important for reactivating caspases...

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IL2RA
Rabu, 2026-02-25 16:33:28

(IL2RG), constitute the high-affinity IL-2 receptor complex (Kd ~10−11M). Homodimeric alpha chains (IL2RA) result in low-affinity receptor (Kd ~10−8M) with...

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Interleukin 35
Rabu, 2026-04-29 05:37:27

of IL-12Rβ2 and IL-27Rα (otherwise known as WSX-1). Both hetero- and homodimeric T cell IL-35 receptors cause intracellular signaling via the JAK-STAT...

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Glycerate dehydrogenase
Kamis, 2026-03-12 21:45:44

function of these enzymes. It has been shown that these proteins are homodimeric enzymes. This means that 2 identical proteins are linked forming one...

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Olivetol
Sabtu, 2025-10-04 16:07:13

PKS named olivetol synthase (OLS) from Cannabis sativa. This PKS is a homodimeric protein that consists of a 385 amino acid polypeptide with a molecular...

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FKBP1A
Minggu, 2025-09-14 08:47:16

COMPLEXED WITH 4-HYDROXY-2-BUTANONE 1eym: FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX 1f40: SOLUTION STRUCTURE OF FKBP12 COMPLEXED WITH GPI-1046, A...

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Killer activation receptor
Kamis, 2025-10-09 18:49:13

which are NKG2D and CD94/NKG2C. NKG2D, which doesn't bind to CD94, is a homodimeric lectin-like receptor. CD94/NKG2C consists in a complex formed by the...

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Tyrosine–tRNA ligase
Kamis, 2026-04-30 15:38:20

structure shows that the group I intron binds across the two subunits of the homodimeric protein with a newly evolved RNA-binding surface distinct from that which...

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Myelin-associated glycoprotein
Minggu, 2025-11-23 23:19:24

has an extended conformation of five immunoglobulin (Ig) domains and a homodimeric arrangement involving membrane-proximal domains Ig4 and Ig5. MAG-oligosaccharide...

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Three-finger toxin
Jumat, 2026-05-22 20:24:51

(March 2010). "Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra)"...

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Fatty acid synthase
Sabtu, 2025-07-19 12:48:03

(February 1998). "Differential affinity labeling of the two subunits of the homodimeric animal fatty acid synthase allows isolation of heterodimers consisting...

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Malate dehydrogenase
Sabtu, 2026-01-17 01:38:27

alpha+beta fold. In most organisms, malate dehydrogenase (MDH) exists as a homodimeric molecule and is closely related to lactate dehydrogenase (LDH) in structure...

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Glutamate decarboxylase
Jumat, 2026-06-05 05:06:00

however their function, if any, is unknown. Both isoforms of GAD are homodimeric structures, consisting of three primary domains: the PLP, C-terminal...

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ACY1
Sabtu, 2025-07-19 12:00:21

in humans is encoded by the ACY1 gene. Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino...

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Fluorine compounds
Rabu, 2026-05-27 20:57:20

Schlöder, T.; Riedel, S. (2012). "Investigation of Heterodimeric and Homodimeric Radical Cations of the Series: [F2O2]+, [F2Cl2]+, [Cl2O2]+, [F4]+, and...

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AKR7A2
Minggu, 2025-12-28 07:13:10

PMID 9823300. Kelly VP, Sherratt PJ, Crouch DH, Hayes JD (2002). "Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate...

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H+, Na+-translocating pyrophosphatase family
Jumat, 2026-05-15 12:25:38

archaea and eukaryotes. These H+ pumping enzymes, which are probably homodimeric, have been reported to fall into two phylogenetic subfamilies. One subfamily...

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S-ribosylhomocysteine lyase
Minggu, 2023-12-03 11:25:51

and LuxS. This enzyme participates in methionine metabolism. LuxS is a homodimeric iron-dependent metalloenzyme containing two identical tetrahedral metal-binding...

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Lysyl oxidase
Sabtu, 2025-07-19 13:25:18

cancerous. In the yeast species Pichia pastoris, lysyl oxidase constitutes a homodimeric structure. Each monomer consists of an active site that includes a Cu(II)...

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List of Kolkata Presidencians
Jumat, 2026-06-05 02:06:46

chemical biologist, known for his studies on UDP-glucose 4-epimerase, a homodimeric epimerase found in cells and his work on Leishmania donovani, the protozoal...

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Leukotriene C4 synthase
Sabtu, 2025-07-19 13:19:52

homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits". Proc. Natl. Acad...

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Genetic engineering techniques
Jumat, 2026-02-20 14:53:22

GH, Belfort M, Wende W, Pingoud A (August 2006). "From monomeric to homodimeric endonucleases and back: engineering novel specificity of LAGLIDADG enzymes"...

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Asymmetric addition of dialkylzinc compounds to aldehydes
Jumat, 2025-12-05 11:07:53

reaction are controlled by the relative concentrations of hetero and homodimeric catalytic complexes; that is, the system displays autocatalysis because...

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Creatinase
Kamis, 2026-03-26 03:57:47

This gene has also been cloned into Escherichia coli. Creatinase is a homodimeric enzyme with a calculated molecular mass of approximately 94,000 ± 2,000...

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Janus kinase 3
Rabu, 2025-10-22 02:52:41

involvement with JAK kinases Type Subgroup Cytokine Receptor JAK Kinase I homodimeric EPO, TPO, GH, G-CSF JAK2 uses common beta chain (CSF2RΒ) IL-3, IL-5,...

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Beta-ketoacyl-ACP synthase
Sabtu, 2025-08-02 19:31:45

beta-ketoacyl-ACP synthases I and II of E. coli revealed that both are homodimeric, but synthase II is slightly larger. However, even though they are both...

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SULT1C2
Sabtu, 2025-07-19 14:25:39

PMID 11535246. Kiehlbauch CC, Lam YF, Ringer DP (August 1995). "Homodimeric and heterodimeric aryl sulfotransferases catalyze the sulfuric acid esterification...

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Sedoheptulose-bisphosphatase
Minggu, 2025-07-20 14:41:10

hydrolase. This enzyme participates in the Calvin cycle. SBPase is a homodimeric protein, meaning that it is made up of two identical subunits. The size...

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Gating (electrophysiology)
Minggu, 2026-03-15 00:25:12

proteins, functionally categories into channel or transporter. They share homodimeric structure with independent ion permeation pathway in each of the subunit...

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Chalcone synthase
Minggu, 2026-01-25 23:40:26

molecules of coenzyme A and one unit of naringenin chalcone. CHS exists as a homodimeric protein with each monomer approximately 42-45 kDa in size. Each monomer...

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P-type ATPase
Rabu, 2026-05-06 23:35:03

report suggests that this sarcoplasmic reticulum (SR) Ca2+ ATPase is homodimeric. Crystal structures have shown that the conserved TGES loop of the Ca2+-ATPase...

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Isocitrate dehydrogenase 1
Rabu, 2026-02-11 01:45:19

domains of one subunit and participates in the conformational changes of homodimeric IDH1. Finally, the clasp domains of both subunits intertwine to form...

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N-acetylglucosamine-6-phosphate deacetylase
Minggu, 2026-04-05 02:55:39

specifically in the biosynthesis of amino-sugar-nucleotides. NagA is a homodimeric enzyme with two domains in each dimer of the structure. Each domain I...

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Interleukin 17
Rabu, 2026-06-03 22:16:42

cells. IL-17(A) is a 155-amino acid protein that is a disulfide-linked, homodimeric, secreted glycoprotein with a molecular mass of 35 kDa. Each subunit...

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Jonathan M. Scholey
Selasa, 2026-05-12 04:08:14

went on to demonstrate that kinesin-2 exists in both heterotrimeric and homodimeric forms in Caenorhabditis elegans sensory neuronal cilia, where the two...

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Glutamate–cysteine ligase
Minggu, 2025-07-20 15:03:47

toxic insults. The plant glutamate cysteine ligase is a redox-sensitive homodimeric enzyme, conserved in the plant kingdom. In an oxidizing environment,...

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Deoxyribonuclease
Jumat, 2026-03-27 17:42:19

residues Gly97 to Gly102 (yellow). DNase II Structure: DNase II contains a homodimeric quaternary structure that is capable of binding double-stranded DNA within...

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Iron/lead transporter
Rabu, 2026-05-06 02:53:13

FetP binds Cu2+ and Mn2+ at two different sites, 1.3 Å apart, in this homodimeric protein. The 3-d structure with two Cu2+ bound to each of the two subunits...

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Anion exchange protein 3
Sabtu, 2026-04-18 04:54:17

gene. Cryo-electron microscopy studies have revealed that AE3 forms a homodimeric complex, structurally similar to other members of the SLC4 family, such...

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RFX2
Jumat, 2025-07-18 01:09:48

transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol. Cell. Biol. 14 (2): 1230–44...

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GSTM4
Minggu, 2025-11-23 06:11:51

v t e PDB gallery 4gtu: LIGAND-FREE HOMODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M4-4...

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Cadherin
Rabu, 2026-01-21 22:34:39

upon the formation of two identical subunits, known as homodimers. The homodimeric cadherins create cell-cell adhesion with cadherins present in the membranes...

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RFX4
Jumat, 2025-11-07 07:10:13

transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol. Cell. Biol. 14 (2): 1230–44...

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Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific)
Minggu, 2025-08-03 20:17:37

Ko TP, Kuo CJ, Guo RT, Chou CC, Liang PH, Wang AH (December 2005). "Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon...

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APC superfamily
Jumat, 2025-05-23 17:18:33

TMS12, non-participants in this repeat, provide most of the 2,500 Å 2 homodimeric interface. AdiC mirrors the common fold observed unexpectedly in four...

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Metabotropic glutamate receptor 1
Sabtu, 2025-07-19 13:30:43

dimeric complex postsynaptic density membrane G protein-coupled receptor homodimeric complex plasma membrane integral component of plasma membrane dendrite...

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Histidinol dehydrogenase
Jumat, 2025-11-21 21:46:29

ion is held in place by His262, Gln259, Asp360 and His419 (which, in homodimeric histidinol dehydrogenases, comes from the other monomer). Histidinol...

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Glutathione S-transferase
Selasa, 2025-09-30 00:08:35

N-terminal domain. Both subunits of the GST dimer, whether hetero- or homodimeric in nature, contain a single nonsubstrate binding site, as well as a GSH-binding...

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Retinoid X receptor alpha
Minggu, 2026-05-31 04:34:33

v t e PDB gallery 1by4: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 1dkf: CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR...

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RFX1
Rabu, 2025-10-22 00:16:15

transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol Cell Biol. 14 (2): 1230–44...

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TRNA-intron endonuclease
Rabu, 2026-02-04 02:31:49

Each α subunit is made up of five α helices and mixed β sheets. The homodimeric tRNA-intron lyase, α′2  is composed of two α′ subunits that appear to...

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Serine C-palmitoyltransferase
Senin, 2025-08-18 12:51:19

(April 2003). "Bacterial serine palmitoyltransferase: a water-soluble homodimeric prototype of the eukaryotic enzyme". Biochimica et Biophysica Acta (BBA)...

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Threonine–tRNA ligase
Rabu, 2025-12-31 12:14:30

synthetase (TARS) from Escherichia coli is encoded by the thrS gene. It is a homodimeric enzyme that aminoacylates tRNA(Thr) with the amino acid threonine. In...

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RFX3
Kamis, 2025-12-18 14:33:51

transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol Cell Biol. 14 (2): 1230–44...

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Bacterial glutathione transferase
Minggu, 2025-11-23 05:07:37

such reactions. Bacterial glutathione transferases of all classes are homodimeric enzymes (although heterodimeric isozymes of certain classes are also...

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Oncostatin M
Sabtu, 2026-05-16 10:17:01

uncharged residue), namely Y905 and Y915. Cytokines that signal via homodimeric complexes of LIFR or OSMR (i.e. devoid of gp130) are currently unknown...

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Uroporphyrinogen III decarboxylase
Kamis, 2026-05-28 03:52:21

is encoded by the UROD gene. Uroporphyrinogen III decarboxylase is a homodimeric enzyme (PDB: 1URO​) that catalyzes the fifth step in heme biosynthesis...

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STC1
Senin, 2025-09-22 00:22:06

humans it is encoded by the STC1 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have...

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BCKDHA
Rabu, 2025-07-16 23:38:10

a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). The reaction is irreversible...

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Inositol monophosphatase 1
Minggu, 2025-09-28 09:46:53

is encoded by the IMPA1 gene. Inositol monophosphatase 1 (IMPA1) is a homodimeric enzyme with each subunit consisting of approximately 277 amino acids...

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Cooperative binding
Kamis, 2026-02-26 22:01:46

the binding of transcription factors were also documented, as for the homodimeric repressor of the Pseudomonas putida cytochrome P450cam hydroxylase operon...

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PEPD
Selasa, 2025-10-21 23:25:24

ɑ-helices and one antiparallel β-sheet. Prolidase enzyme is considered homodimeric, meaning it is formed by two identical polypeptide chains. There are...

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Discovery and development of HIV-protease inhibitors
Minggu, 2026-05-31 21:46:14

designed using the same principle. The HIV protease is a C2-symmetric homodimeric enzyme consisting of two 99 amino acid monomers. Each monomer contributes...

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SAG1 protein domain
Rabu, 2023-11-29 10:49:21

Extracellular matrix. The structure of the immunodominant SAG1 antigen reveals a homodimeric configuration. This family of surface antigens is found in other apicomplexans...

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Retinoid X receptor gamma
Sabtu, 2025-07-19 14:09:18

v t e PDB gallery 1by4: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 1dsz: STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER...

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TCF21 (gene)
Sabtu, 2026-02-14 19:36:09

complex was generated with the probe that migrated faster than the E12 homodimeric complex alone, representing the binding of capsulin/E12 heterodimers...

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Aquicella
Kamis, 2025-07-17 23:21:33

domain-containing protein, pyruvate dehydrogenase (acetyl-transferring), homodimeric type, c-type cytochrome and response regulator transcription factor....

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ERCC4
Minggu, 2026-05-10 13:14:47

Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 2aq0: Solution structure of the human homodimeric dna repair protein XPF...

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Theta defensin
Minggu, 2025-09-28 12:19:34

Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME (February 2002). "Homodimeric θ-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial...

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Cluster of Excellence Frankfurt Macromolecular Complexes
Senin, 2026-06-01 02:52:19

ABC transporters. Based on real-time 31P-MAS-NMR they found that the homodimeric lipid A flippase MsbA is able to catalyze a reverse adenylate kinase-like...

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Sulfatide
Kamis, 2026-02-19 23:27:35

reaction is catalyzed by cerebroside sulfotransferase (CST). CST is a homodimeric protein that is found in the Golgi apparatus. It has been demonstrated...

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Bornyl diphosphate synthase
Selasa, 2026-05-12 17:09:19

of David W. Christianson at the University of Pennsylvania. BPPS is a homodimeric isomerase, with each of the two monomers containing two α-helical domains...

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KCNK13
Senin, 2026-01-26 11:14:47

Ribbon structure of homodimeric two-pore potassium channel K2P13 (THIK-1)....

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Cadherin–catenin complex in learning and memory
Rabu, 2026-01-28 02:30:15

will associate with the cadherin-catenin complex via β-catenins. In homodimeric form, α-catenins do not bind β- catenins, but preferentially bind F-actin...

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Cell division control protein 4
Jumat, 2026-03-20 16:16:21

domain. In yeast Cdc4, the D domain protomers arrange in a superhelical homodimeric manner. SCF (Cdc4) dimerization hardly affects the affinity for target...

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Aldehyde ferredoxin oxidoreductase
Sabtu, 2024-06-22 06:50:50

ferredoxin oxidoreductase to metabolize the amino acid carbon source. AOR is homodimeric. Each 67kDa subunit contains 1 tungsten and 4-5 Iron atoms. The two subunits...

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SMC protein
Kamis, 2026-06-04 00:48:01

such as SMC–ScpAB, MukBEF, and MksBEF. However, unlike their typically homodimeric prokaryotic counterparts, both the SMC and kite subunits in the SMC5/6...

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RANGAP1
Kamis, 2025-07-17 01:27:24

enzyme that in humans is encoded by the RANGAP1 gene. RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN...

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Retinoid X receptor beta
Sabtu, 2025-07-19 14:09:16

v t e PDB gallery 1by4: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 1dsz: STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER...

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ABCB9
Senin, 2025-08-18 17:52:35

(2005). "Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)". J. Biol. Chem. 280...

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