Search Results: Homodimeric
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Protein dimer
Senin, 2026-03-02 11:38:50exception is dimers that are linked by disulfide bridges such as the homodimeric protein NEMO. Some proteins contain specialized domains to ensure dimerization...
Click to read more »Racemic crystallography
Selasa, 2025-11-04 12:38:39Racemic crystal structure of homodimeric Rv1738 from Mycobacterium tuberculosis...
Click to read more »Two-component regulatory system
Sabtu, 2025-10-04 03:27:18regulator (RR) by a histidine kinase (HK). Histidine kinases are typically homodimeric transmembrane proteins containing a histidine phosphotransfer domain...
Click to read more »King cobra
Sabtu, 2026-05-16 07:39:00R. M. (2010). "Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)"...
Click to read more »Anoxygenic photosynthesis
Rabu, 2025-12-10 05:51:23Sen-Fang; Qin, Xiaochun (2022-12-14). "Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c". Nature Communications. 13 (1):...
Click to read more »Alkaline phosphatase
Jumat, 2026-05-15 12:31:37hemoglobinuria and acute myelogenous leukaemia. Alkaline phosphatase is homodimeric enzyme, meaning it is formed with two molecules. Three metal ions, two...
Click to read more »Rop protein
Jumat, 2023-08-18 14:38:21preprimer RNA, RNA II, and its antisense RNA, RNA I. Structurally, Rop is a homodimeric four-helix bundle protein formed by the antiparallel interaction of two...
Click to read more »Polyketide synthase
Senin, 2026-05-18 22:18:48or dissociable molecular assemblies; type III PKSs exist as smaller homodimeric proteins. PKSs can be classified into three types: Type I PKSs Large...
Click to read more »TGF beta receptor
Minggu, 2025-10-19 03:00:52low affinity for TGFβ2. TGFβR3 (β-glycan) has a high affinity for both homodimeric TGFβ1 and TGFβ2 and in addition the heterodimer TGF-β1.2. The TGFβ receptors...
Click to read more »Fluorine
Jumat, 2026-05-29 05:30:52Schlöder, T.; Riedel, S. (2012). "Investigation of Heterodimeric and Homodimeric Radical Cations of the Series: [F2O2]+, [F2Cl2]+, [Cl2O2]+, [F4]+, and...
Click to read more »UDP-glucose 4-epimerase
Jumat, 2025-09-26 20:19:42(EC 5.1.3.2), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This...
Click to read more »Enterococcus faecalis
Minggu, 2026-05-10 02:20:38used to show detailed insights into the unfolding of the E. faecalis homodimeric repressor protein CylR2. The E. faecalis genome consists of 3.22 million...
Click to read more »Lysibody
Jumat, 2026-03-20 21:58:02held together by hinge-region disulfide bonds. Thus, lysibodies are homodimeric hybrid immunoglobulin G molecules that can bind with high affinity and...
Click to read more »Microprotein
Senin, 2026-05-25 05:11:46post-translational regulators. Microproteins disrupt the formation of heterodimeric, homodimeric, or multimeric complexes. Furthermore, microproteins can interact with...
Click to read more »Sex hormone–binding globulin
Rabu, 2026-05-13 17:36:47site and turns off production of SHBG. Sex hormone-binding globulin is homodimeric, meaning it has two identical peptide chains making up its structure...
Click to read more »Intracellular antibody-mediated degradation
Jumat, 2021-09-03 21:51:44structure of two molecules of the C-terminal PRYSPRY domain of TRIM21 (top right and top left) complexed with homodimeric Ig gamma-1 chain C region (center)....
Click to read more »Restriction enzyme
Senin, 2026-04-27 15:31:26Type II site-specific deoxyribonuclease-like Structure of the homodimeric restriction enzyme EcoRI (cyan and green cartoon diagram) bound to double stranded...
Click to read more »Uteroglobin
Minggu, 2026-04-19 01:02:59dimeric proteins found only in mammals. This antiparallel disulfide linked homodimeric protein is multifunctional and found in various tissues in various names...
Click to read more »Phenylalanine hydroxylase
Rabu, 2025-07-30 18:07:21whereas eukaryotic PAH exists in an equilibrium between homotetrameric and homodimeric forms. The dimerization interface is composed of symmetry-related loops...
Click to read more »OXCT1
Kamis, 2025-07-17 01:12:31the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic...
Click to read more »Iron superoxide dismutase
Jumat, 2025-07-04 19:38:46connecting the β1 and β2 strands within the enzyme. FeSOD can also exist in homodimeric or homotetrameric forms, depending on the organism. Like its structural...
Click to read more »Shugoshin N terminal protein domain
Kamis, 2024-02-22 04:30:23Shugoshin protein is a coiled-coil which can be further described as a homodimeric parallel coiled-coil. Kitajima TS, Kawashima SA, Watanabe Y (February...
Click to read more »Spätzle (protein)
Kamis, 2025-10-23 15:23:41the final spz[221-326] (Spaetzle C-106) part as the mature protein. Homodimeric spz binds to a dimeric toll receptor in fruit flies and related organisms...
Click to read more »Glur2 RNA editing
Sabtu, 2026-01-24 12:01:20combine to form tetramers. They are usually heterotrimeric but can be homodimeric. Each AMPAR has four sites to which an agonist (such as L-glutamate)...
Click to read more »KIF17
Sabtu, 2025-07-19 13:16:23kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors...
Click to read more »FYVE domain
Jumat, 2025-09-19 23:45:11Sudharshan E, et al. (November 2001). "Multivalent endosome targeting by homodimeric EEA1". Mol. Cell. 8 (5): 947–58. doi:10.1016/S1097-2765(01)00385-9. PMID 11741531...
Click to read more »PYGL
Selasa, 2026-06-02 12:38:53humans is encoded by the PYGL gene on chromosome 14. This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to...
Click to read more »ZHX2
Rabu, 2025-07-16 05:29:21The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear...
Click to read more »ZP3
Senin, 2026-03-30 22:45:30with the ZP-N domain of a second molecule to generate an antiparallel homodimeric arrangement required for protein secretion. The Zona Pellucida (ZP) is...
Click to read more »GOT2
Senin, 2026-01-26 09:41:17a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation...
Click to read more »CNDP1
Kamis, 2025-12-18 19:07:29family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains...
Click to read more »Glutathione synthetase
Minggu, 2025-07-20 15:05:39symptoms in plants and human beings alike. In eukaryotes, this is a homodimeric enzyme. The substrate-binding domain has a three-layer alpha/beta/alpha...
Click to read more »Amar Nath Bhaduri
Jumat, 2026-02-06 05:26:01chemical biologist, known for his studies on UDP-glucose 4-epimerase, a homodimeric epimerase found in cells and his work on Leishmania donovani, the protozoal...
Click to read more »Aspartate racemase
Minggu, 2025-09-28 10:07:31This protein shares nearly identical enzymological properties with homodimeric aspartate racemase isolated from Streptococcus thermophilus, but has...
Click to read more »HAMP domain
Jumat, 2024-10-04 17:16:22domains and thus regulates the phosphorylation or methylation activity of homodimeric receptors. Aravind L, Ponting CP (July 1999). "The cytoplasmic helical...
Click to read more »Immunoglobulin light chain
Kamis, 2026-03-05 09:53:12as part of their adaptive immune systems, a functional heavy-chain homodimeric antibody-like molecule referred to as IgNAR (immunoglobulin new antigen...
Click to read more »Lanthanide-dependent methanol dehydrogenase
Minggu, 2026-05-10 11:23:48AHDs revealed more about the biological activity of lanthanides. In the homodimeric Ce3+-dependent methanol dehydrogenase sampled from methylacidiphilum...
Click to read more »Α-Galactosidase
Jumat, 2026-06-05 00:10:40internal insertion region to form its dimer interface. This enzyme is a homodimeric glycoprotein that hydrolyses the terminal α-galactosyl moieties from...
Click to read more »Meganuclease
Selasa, 2026-05-19 23:34:44have developed a collection of over 20,000 protein domains from the homodimeric meganuclease I-CreI as well as from other meganucleases scaffolds. They...
Click to read more »STC2
Sabtu, 2025-07-19 14:23:33in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have...
Click to read more »Glycerol kinase
Senin, 2022-05-09 02:47:39there were 20 structures of this protein in the PDB, most of which are homodimeric. Glycerol Kinase Glycerol+Kinase at the U.S. National Library of Medicine...
Click to read more »ABCD4
Rabu, 2025-07-16 04:20:18which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane...
Click to read more »Peridinin-chlorophyll-protein complex
Jumat, 2022-02-25 18:22:36forms, a homodimeric form composed of two 15-kD monomers, and a monomeric form of around 32kD believed to have evolved from the homodimeric form via gene...
Click to read more »ABCD1
Kamis, 2025-07-31 20:30:43which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely...
Click to read more »Carbon monoxide dehydrogenase
Senin, 2026-03-23 04:31:31their phylogenetic relationship Homodimeric Ni,Fe-CODHs contain five-metal clusters. They exist either in a homodimeric form (also called monofunctional)...
Click to read more »GOT1
Senin, 2026-01-26 09:38:30metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Click on genes, proteins and metabolites below...
Click to read more »Ribonuclease III
Rabu, 2026-04-08 23:13:51domain structure. Class 1 RNase III Class 1 RNase III enzymes have a homodimeric structure whose function is to cleave dsRNA into multiple subunits. It...
Click to read more »Non-homologous end joining
Minggu, 2026-01-04 17:21:50dormant cells. The archaeal NHEJ system in Methanocella paludicola have a homodimeric Ku, but the three functions of LigD are broken up into three single-domain...
Click to read more »Anion exchanger family
Sabtu, 2026-04-18 04:35:1622992757; 29% identity in 90 residues). Animal AE proteins consist of homodimeric complexes of integral membrane proteins that vary in size from about...
Click to read more »Lymphangioleiomyomatosis
Senin, 2026-05-25 13:40:48of chylous effusions and lymphatic involvement). VEGF-D is a secreted homodimeric glycoprotein and a member of the VEGF family of growth factors, is known...
Click to read more »Influenza non-structural protein
Jumat, 2020-09-11 19:46:25Influenza non-structural protein (NS1) is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds...
Click to read more »ZHX1
Jumat, 2025-07-18 01:53:28The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear...
Click to read more »Nitrate reductase
Minggu, 2026-05-10 23:21:05weissflogii. The nitrate reductase of higher plants, algae, and fungi is a homodimeric cytosolic protein with five conserved domains in each monomer: 1) an...
Click to read more »Nucleoid
Kamis, 2026-06-04 08:18:53structuring protein (H-NS) from other NAPs is the ability to switch from the homodimeric form at relatively low concentrations (<1 × 10−5 M) to an oligomeric...
Click to read more »Shelterin
Sabtu, 2024-09-21 05:04:01than TPP1 and POT1. TRF1 (Telomere Repeat binding Factor 1): TRF1 is a homodimeric protein that binds to the double-stranded TTAGGG region of the telomere...
Click to read more »Trefoil knot fold
Senin, 2024-07-15 13:27:56E. (2006). "Probing Nature's Knots: The Folding Pathway of a Knotted Homodimeric Protein". Journal of Molecular Biology. 359 (5): 1420–1436. doi:10.1016/j...
Click to read more »CooA
Senin, 2025-12-22 11:58:21N-terminal amine as ligands in both ferric and ferrous states. CooA is a homodimeric, heme-containing transcription factor of the CAP/CRP family, with each...
Click to read more »Nitrogenase
Sabtu, 2026-03-07 16:34:36ambient temperatures. A usual assembly consists of two components: The homodimeric Fe-only protein, the reductase which has a high reducing power and is...
Click to read more »Geranyltranstransferase
Sabtu, 2023-08-26 21:11:44geranyltranstransferase, is well characterized. FPPS is a ~30 kDa Mg2+ dependent homodimeric enzyme that synthesizes (E, E)-farnesyl pyrophosphate in a successive...
Click to read more »BCR (gene)
Kamis, 2025-07-17 22:47:42of the BCR-ABL oncoprotein (BCR30-65) resulted in a new pH-sensitive homodimeric antiparallel coiled coil. Although the BCR-ABL fusion protein has been...
Click to read more »Leucine zipper
Rabu, 2026-05-06 00:27:58higher evolution complexity. Heterodimeric bZIP proteins differ from homodimeric bZIP and from each other in protein-protein interaction affinity. These...
Click to read more »CD135
Rabu, 2025-08-06 19:03:39ternary complex is formed in which two FLT3 molecules are bridged by one (homodimeric) FLT3L. The formation of such complex brings the two intracellular domains...
Click to read more »ANO1
Minggu, 2025-09-28 14:32:07Markwardt F, Schmalzing G (February 2011). "TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels". Molecular & Cellular Proteomics...
Click to read more »Endoglin
Minggu, 2025-10-12 05:31:15ligand via interaction of two copies of OR1 with the knuckle regions of homodimeric BMP-9. In addition to rationalizing a large number of HHT1 mutations...
Click to read more »3-dehydroquinate dehydratase
Jumat, 2025-07-18 01:04:46enzyme is from Escherichia coli (gene aroD) and related bacteria. It is a homodimeric protein. In fungi, dehydroquinase forms the core of the pentafunctional...
Click to read more »BMPR2
Jumat, 2025-08-08 17:50:35oligomers increase, suggesting that the equilibrium shifts towards the homodimeric form. The low affinity for ligands suggests that BMPR2 may differ from...
Click to read more »S100A6
Sabtu, 2025-07-19 14:13:01NMR, 20 STRUCTURES 1cnp: THE STRUCTURE OF CALCYCLIN REVEALS A NOVEL HOMODIMERIC FOLD FOR S100 CA2+-BINDING PROTEINS, NMR, 22 STRUCTURES 1jwd: Ca2+-induced...
Click to read more »Glutathione S-transferase, C-terminal domain
Jumat, 2025-10-17 20:23:20also form heterodimers of the A1 and A2 or YC1 and YC2 subunits. The homodimeric enzymes display a conserved structural fold. Each monomer is composed...
Click to read more »Platelet-derived growth factor receptor
Rabu, 2025-11-26 11:55:40"Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes". Kidney International. 41 (3): 571–4. doi:10.1038/ki...
Click to read more »CKMT1A
Selasa, 2025-10-21 03:52:14CKMT1A is located in the mitochondrial intermembrane space and form both homodimeric and homooctameric molecules that are readily interconvertible. Like all...
Click to read more »Cobratoxin
Jumat, 2026-01-30 08:36:53form and a disulfide-bound dimeric form. α-Cobratoxin dimers can be homodimeric as well as heterodimeric with cytotoxin 1, cytotoxin 2 and cytotoxin...
Click to read more »Choline kinase
Rabu, 2025-10-01 09:47:33encoded by two separate genes, CHKA and CHKB and are only active in their homodimeric, heterodimeric and oligomeric forms. As of late 2007, six structures...
Click to read more »Bone growth factor
Rabu, 2025-07-16 23:42:17polypeptide chains A and B. The combination of these polypeptides form the homodimeric (AA) or (BB), or heterodimeric (AB) chains of PDGF. Fibroblast growth...
Click to read more »Metastatic breast cancer
Jumat, 2026-06-05 01:52:48in cartilaginous tissues. Endoglin is a cell-surface disulfide-linked homodimeric glycoprotein which binds to integrins and other RGD ligands and is a...
Click to read more »S100 protein
Sabtu, 2025-10-04 15:18:15THP-1 cells. Most S100 proteins consist of two identical polypeptides (homodimeric), which are held together by noncovalent bonds. They are structurally...
Click to read more »ProtCID
Selasa, 2025-10-28 08:52:58structures of homologous proteins. Its main goal is to identify and cluster homodimeric and heterodimeric interfaces observed in multiple crystal forms of homologous...
Click to read more »Galectin-7
Kamis, 2026-05-21 01:58:45Reitzenstein C, Versluis K, Kaltner H, Pieters RJ, et al. (September 2003). "Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human...
Click to read more »KIF3B
Senin, 2026-01-19 12:32:12part of the Kinesin-2 family of kinesins that form heterotrimeric or homodimeric complexes. Expression of the three motor subunits of heterotrimeric kinesin-2...
Click to read more »ABCD2
Sabtu, 2025-07-19 11:58:53which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane...
Click to read more »Interferon-gamma receptor
Selasa, 2025-10-21 19:38:55Tyrosine-phosphorylated Stat1 molecules dissociate from their receptor tether and form homodimeric complexes. Activated Stat1 translocates to the nucleus and, after binding...
Click to read more »Interferon gamma receptor (IFNGR1) family
Kamis, 2025-02-27 16:28:30homodimers, whereas the cellular IFN-gammaR dimerises only upon binding the homodimeric IFN-gamma. The existence of the virus protein as a dimer in the absence...
Click to read more »PLOD3
Rabu, 2025-07-16 05:10:20the PLOD3 gene. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum...
Click to read more »ABCD3
Sabtu, 2025-07-19 23:08:43which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely...
Click to read more »Peptidomimetic
Senin, 2026-06-01 10:12:44cooperativity results from the molecule's ability to also mimic the homodimeric structure of Smac, which is functionally important for reactivating caspases...
Click to read more »IL2RA
Rabu, 2026-02-25 16:33:28(IL2RG), constitute the high-affinity IL-2 receptor complex (Kd ~10−11M). Homodimeric alpha chains (IL2RA) result in low-affinity receptor (Kd ~10−8M) with...
Click to read more »Interleukin 35
Rabu, 2026-04-29 05:37:27of IL-12Rβ2 and IL-27Rα (otherwise known as WSX-1). Both hetero- and homodimeric T cell IL-35 receptors cause intracellular signaling via the JAK-STAT...
Click to read more »Glycerate dehydrogenase
Kamis, 2026-03-12 21:45:44function of these enzymes. It has been shown that these proteins are homodimeric enzymes. This means that 2 identical proteins are linked forming one...
Click to read more »Olivetol
Sabtu, 2025-10-04 16:07:13PKS named olivetol synthase (OLS) from Cannabis sativa. This PKS is a homodimeric protein that consists of a 385 amino acid polypeptide with a molecular...
Click to read more »FKBP1A
Minggu, 2025-09-14 08:47:16COMPLEXED WITH 4-HYDROXY-2-BUTANONE 1eym: FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX 1f40: SOLUTION STRUCTURE OF FKBP12 COMPLEXED WITH GPI-1046, A...
Click to read more »Killer activation receptor
Kamis, 2025-10-09 18:49:13which are NKG2D and CD94/NKG2C. NKG2D, which doesn't bind to CD94, is a homodimeric lectin-like receptor. CD94/NKG2C consists in a complex formed by the...
Click to read more »Tyrosine–tRNA ligase
Kamis, 2026-04-30 15:38:20structure shows that the group I intron binds across the two subunits of the homodimeric protein with a newly evolved RNA-binding surface distinct from that which...
Click to read more »Myelin-associated glycoprotein
Minggu, 2025-11-23 23:19:24has an extended conformation of five immunoglobulin (Ig) domains and a homodimeric arrangement involving membrane-proximal domains Ig4 and Ig5. MAG-oligosaccharide...
Click to read more »Three-finger toxin
Jumat, 2026-05-22 20:24:51(March 2010). "Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra)"...
Click to read more »Fatty acid synthase
Sabtu, 2025-07-19 12:48:03(February 1998). "Differential affinity labeling of the two subunits of the homodimeric animal fatty acid synthase allows isolation of heterodimers consisting...
Click to read more »Malate dehydrogenase
Sabtu, 2026-01-17 01:38:27alpha+beta fold. In most organisms, malate dehydrogenase (MDH) exists as a homodimeric molecule and is closely related to lactate dehydrogenase (LDH) in structure...
Click to read more »Glutamate decarboxylase
Jumat, 2026-06-05 05:06:00however their function, if any, is unknown. Both isoforms of GAD are homodimeric structures, consisting of three primary domains: the PLP, C-terminal...
Click to read more »ACY1
Sabtu, 2025-07-19 12:00:21in humans is encoded by the ACY1 gene. Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino...
Click to read more »Fluorine compounds
Rabu, 2026-05-27 20:57:20Schlöder, T.; Riedel, S. (2012). "Investigation of Heterodimeric and Homodimeric Radical Cations of the Series: [F2O2]+, [F2Cl2]+, [Cl2O2]+, [F4]+, and...
Click to read more »AKR7A2
Minggu, 2025-12-28 07:13:10PMID 9823300. Kelly VP, Sherratt PJ, Crouch DH, Hayes JD (2002). "Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate...
Click to read more »H+, Na+-translocating pyrophosphatase family
Jumat, 2026-05-15 12:25:38archaea and eukaryotes. These H+ pumping enzymes, which are probably homodimeric, have been reported to fall into two phylogenetic subfamilies. One subfamily...
Click to read more »S-ribosylhomocysteine lyase
Minggu, 2023-12-03 11:25:51and LuxS. This enzyme participates in methionine metabolism. LuxS is a homodimeric iron-dependent metalloenzyme containing two identical tetrahedral metal-binding...
Click to read more »Lysyl oxidase
Sabtu, 2025-07-19 13:25:18cancerous. In the yeast species Pichia pastoris, lysyl oxidase constitutes a homodimeric structure. Each monomer consists of an active site that includes a Cu(II)...
Click to read more »List of Kolkata Presidencians
Jumat, 2026-06-05 02:06:46chemical biologist, known for his studies on UDP-glucose 4-epimerase, a homodimeric epimerase found in cells and his work on Leishmania donovani, the protozoal...
Click to read more »Leukotriene C4 synthase
Sabtu, 2025-07-19 13:19:52homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits". Proc. Natl. Acad...
Click to read more »Genetic engineering techniques
Jumat, 2026-02-20 14:53:22GH, Belfort M, Wende W, Pingoud A (August 2006). "From monomeric to homodimeric endonucleases and back: engineering novel specificity of LAGLIDADG enzymes"...
Click to read more »Asymmetric addition of dialkylzinc compounds to aldehydes
Jumat, 2025-12-05 11:07:53reaction are controlled by the relative concentrations of hetero and homodimeric catalytic complexes; that is, the system displays autocatalysis because...
Click to read more »Creatinase
Kamis, 2026-03-26 03:57:47This gene has also been cloned into Escherichia coli. Creatinase is a homodimeric enzyme with a calculated molecular mass of approximately 94,000 ± 2,000...
Click to read more »Janus kinase 3
Rabu, 2025-10-22 02:52:41involvement with JAK kinases Type Subgroup Cytokine Receptor JAK Kinase I homodimeric EPO, TPO, GH, G-CSF JAK2 uses common beta chain (CSF2RΒ) IL-3, IL-5,...
Click to read more »Beta-ketoacyl-ACP synthase
Sabtu, 2025-08-02 19:31:45beta-ketoacyl-ACP synthases I and II of E. coli revealed that both are homodimeric, but synthase II is slightly larger. However, even though they are both...
Click to read more »SULT1C2
Sabtu, 2025-07-19 14:25:39PMID 11535246. Kiehlbauch CC, Lam YF, Ringer DP (August 1995). "Homodimeric and heterodimeric aryl sulfotransferases catalyze the sulfuric acid esterification...
Click to read more »Sedoheptulose-bisphosphatase
Minggu, 2025-07-20 14:41:10hydrolase. This enzyme participates in the Calvin cycle. SBPase is a homodimeric protein, meaning that it is made up of two identical subunits. The size...
Click to read more »Gating (electrophysiology)
Minggu, 2026-03-15 00:25:12proteins, functionally categories into channel or transporter. They share homodimeric structure with independent ion permeation pathway in each of the subunit...
Click to read more »Chalcone synthase
Minggu, 2026-01-25 23:40:26molecules of coenzyme A and one unit of naringenin chalcone. CHS exists as a homodimeric protein with each monomer approximately 42-45 kDa in size. Each monomer...
Click to read more »P-type ATPase
Rabu, 2026-05-06 23:35:03report suggests that this sarcoplasmic reticulum (SR) Ca2+ ATPase is homodimeric. Crystal structures have shown that the conserved TGES loop of the Ca2+-ATPase...
Click to read more »Isocitrate dehydrogenase 1
Rabu, 2026-02-11 01:45:19domains of one subunit and participates in the conformational changes of homodimeric IDH1. Finally, the clasp domains of both subunits intertwine to form...
Click to read more »N-acetylglucosamine-6-phosphate deacetylase
Minggu, 2026-04-05 02:55:39specifically in the biosynthesis of amino-sugar-nucleotides. NagA is a homodimeric enzyme with two domains in each dimer of the structure. Each domain I...
Click to read more »Interleukin 17
Rabu, 2026-06-03 22:16:42cells. IL-17(A) is a 155-amino acid protein that is a disulfide-linked, homodimeric, secreted glycoprotein with a molecular mass of 35 kDa. Each subunit...
Click to read more »Jonathan M. Scholey
Selasa, 2026-05-12 04:08:14went on to demonstrate that kinesin-2 exists in both heterotrimeric and homodimeric forms in Caenorhabditis elegans sensory neuronal cilia, where the two...
Click to read more »Glutamate–cysteine ligase
Minggu, 2025-07-20 15:03:47toxic insults. The plant glutamate cysteine ligase is a redox-sensitive homodimeric enzyme, conserved in the plant kingdom. In an oxidizing environment,...
Click to read more »Deoxyribonuclease
Jumat, 2026-03-27 17:42:19residues Gly97 to Gly102 (yellow). DNase II Structure: DNase II contains a homodimeric quaternary structure that is capable of binding double-stranded DNA within...
Click to read more »Iron/lead transporter
Rabu, 2026-05-06 02:53:13FetP binds Cu2+ and Mn2+ at two different sites, 1.3 Å apart, in this homodimeric protein. The 3-d structure with two Cu2+ bound to each of the two subunits...
Click to read more »Anion exchange protein 3
Sabtu, 2026-04-18 04:54:17gene. Cryo-electron microscopy studies have revealed that AE3 forms a homodimeric complex, structurally similar to other members of the SLC4 family, such...
Click to read more »RFX2
Jumat, 2025-07-18 01:09:48transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol. Cell. Biol. 14 (2): 1230–44...
Click to read more »GSTM4
Minggu, 2025-11-23 06:11:51v t e PDB gallery 4gtu: LIGAND-FREE HOMODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M4-4...
Click to read more »Cadherin
Rabu, 2026-01-21 22:34:39upon the formation of two identical subunits, known as homodimers. The homodimeric cadherins create cell-cell adhesion with cadherins present in the membranes...
Click to read more »RFX4
Jumat, 2025-11-07 07:10:13transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol. Cell. Biol. 14 (2): 1230–44...
Click to read more »Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific)
Minggu, 2025-08-03 20:17:37Ko TP, Kuo CJ, Guo RT, Chou CC, Liang PH, Wang AH (December 2005). "Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon...
Click to read more »APC superfamily
Jumat, 2025-05-23 17:18:33TMS12, non-participants in this repeat, provide most of the 2,500 Å 2 homodimeric interface. AdiC mirrors the common fold observed unexpectedly in four...
Click to read more »Metabotropic glutamate receptor 1
Sabtu, 2025-07-19 13:30:43dimeric complex postsynaptic density membrane G protein-coupled receptor homodimeric complex plasma membrane integral component of plasma membrane dendrite...
Click to read more »Histidinol dehydrogenase
Jumat, 2025-11-21 21:46:29ion is held in place by His262, Gln259, Asp360 and His419 (which, in homodimeric histidinol dehydrogenases, comes from the other monomer). Histidinol...
Click to read more »Glutathione S-transferase
Selasa, 2025-09-30 00:08:35N-terminal domain. Both subunits of the GST dimer, whether hetero- or homodimeric in nature, contain a single nonsubstrate binding site, as well as a GSH-binding...
Click to read more »Retinoid X receptor alpha
Minggu, 2026-05-31 04:34:33v t e PDB gallery 1by4: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 1dkf: CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR...
Click to read more »RFX1
Rabu, 2025-10-22 00:16:15transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol Cell Biol. 14 (2): 1230–44...
Click to read more »TRNA-intron endonuclease
Rabu, 2026-02-04 02:31:49Each α subunit is made up of five α helices and mixed β sheets. The homodimeric tRNA-intron lyase, α′2 is composed of two α′ subunits that appear to...
Click to read more »Serine C-palmitoyltransferase
Senin, 2025-08-18 12:51:19(April 2003). "Bacterial serine palmitoyltransferase: a water-soluble homodimeric prototype of the eukaryotic enzyme". Biochimica et Biophysica Acta (BBA)...
Click to read more »Threonine–tRNA ligase
Rabu, 2025-12-31 12:14:30synthetase (TARS) from Escherichia coli is encoded by the thrS gene. It is a homodimeric enzyme that aminoacylates tRNA(Thr) with the amino acid threonine. In...
Click to read more »RFX3
Kamis, 2025-12-18 14:33:51transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins". Mol Cell Biol. 14 (2): 1230–44...
Click to read more »Bacterial glutathione transferase
Minggu, 2025-11-23 05:07:37such reactions. Bacterial glutathione transferases of all classes are homodimeric enzymes (although heterodimeric isozymes of certain classes are also...
Click to read more »Oncostatin M
Sabtu, 2026-05-16 10:17:01uncharged residue), namely Y905 and Y915. Cytokines that signal via homodimeric complexes of LIFR or OSMR (i.e. devoid of gp130) are currently unknown...
Click to read more »Uroporphyrinogen III decarboxylase
Kamis, 2026-05-28 03:52:21is encoded by the UROD gene. Uroporphyrinogen III decarboxylase is a homodimeric enzyme (PDB: 1URO) that catalyzes the fifth step in heme biosynthesis...
Click to read more »STC1
Senin, 2025-09-22 00:22:06humans it is encoded by the STC1 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have...
Click to read more »BCKDHA
Rabu, 2025-07-16 23:38:10a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). The reaction is irreversible...
Click to read more »Inositol monophosphatase 1
Minggu, 2025-09-28 09:46:53is encoded by the IMPA1 gene. Inositol monophosphatase 1 (IMPA1) is a homodimeric enzyme with each subunit consisting of approximately 277 amino acids...
Click to read more »Cooperative binding
Kamis, 2026-02-26 22:01:46the binding of transcription factors were also documented, as for the homodimeric repressor of the Pseudomonas putida cytochrome P450cam hydroxylase operon...
Click to read more »PEPD
Selasa, 2025-10-21 23:25:24ɑ-helices and one antiparallel β-sheet. Prolidase enzyme is considered homodimeric, meaning it is formed by two identical polypeptide chains. There are...
Click to read more »Discovery and development of HIV-protease inhibitors
Minggu, 2026-05-31 21:46:14designed using the same principle. The HIV protease is a C2-symmetric homodimeric enzyme consisting of two 99 amino acid monomers. Each monomer contributes...
Click to read more »SAG1 protein domain
Rabu, 2023-11-29 10:49:21Extracellular matrix. The structure of the immunodominant SAG1 antigen reveals a homodimeric configuration. This family of surface antigens is found in other apicomplexans...
Click to read more »Retinoid X receptor gamma
Sabtu, 2025-07-19 14:09:18v t e PDB gallery 1by4: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 1dsz: STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER...
Click to read more »TCF21 (gene)
Sabtu, 2026-02-14 19:36:09complex was generated with the probe that migrated faster than the E12 homodimeric complex alone, representing the binding of capsulin/E12 heterodimers...
Click to read more »Aquicella
Kamis, 2025-07-17 23:21:33domain-containing protein, pyruvate dehydrogenase (acetyl-transferring), homodimeric type, c-type cytochrome and response regulator transcription factor....
Click to read more »ERCC4
Minggu, 2026-05-10 13:14:47Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 2aq0: Solution structure of the human homodimeric dna repair protein XPF...
Click to read more »Theta defensin
Minggu, 2025-09-28 12:19:34Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME (February 2002). "Homodimeric θ-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial...
Click to read more »Cluster of Excellence Frankfurt Macromolecular Complexes
Senin, 2026-06-01 02:52:19ABC transporters. Based on real-time 31P-MAS-NMR they found that the homodimeric lipid A flippase MsbA is able to catalyze a reverse adenylate kinase-like...
Click to read more »Sulfatide
Kamis, 2026-02-19 23:27:35reaction is catalyzed by cerebroside sulfotransferase (CST). CST is a homodimeric protein that is found in the Golgi apparatus. It has been demonstrated...
Click to read more »Bornyl diphosphate synthase
Selasa, 2026-05-12 17:09:19of David W. Christianson at the University of Pennsylvania. BPPS is a homodimeric isomerase, with each of the two monomers containing two α-helical domains...
Click to read more »KCNK13
Senin, 2026-01-26 11:14:47Ribbon structure of homodimeric two-pore potassium channel K2P13 (THIK-1)....
Click to read more »Cadherin–catenin complex in learning and memory
Rabu, 2026-01-28 02:30:15will associate with the cadherin-catenin complex via β-catenins. In homodimeric form, α-catenins do not bind β- catenins, but preferentially bind F-actin...
Click to read more »Cell division control protein 4
Jumat, 2026-03-20 16:16:21domain. In yeast Cdc4, the D domain protomers arrange in a superhelical homodimeric manner. SCF (Cdc4) dimerization hardly affects the affinity for target...
Click to read more »Aldehyde ferredoxin oxidoreductase
Sabtu, 2024-06-22 06:50:50ferredoxin oxidoreductase to metabolize the amino acid carbon source. AOR is homodimeric. Each 67kDa subunit contains 1 tungsten and 4-5 Iron atoms. The two subunits...
Click to read more »SMC protein
Kamis, 2026-06-04 00:48:01such as SMC–ScpAB, MukBEF, and MksBEF. However, unlike their typically homodimeric prokaryotic counterparts, both the SMC and kite subunits in the SMC5/6...
Click to read more »RANGAP1
Kamis, 2025-07-17 01:27:24enzyme that in humans is encoded by the RANGAP1 gene. RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN...
Click to read more »Retinoid X receptor beta
Sabtu, 2025-07-19 14:09:16v t e PDB gallery 1by4: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 1dsz: STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER...
Click to read more »ABCB9
Senin, 2025-08-18 17:52:35(2005). "Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)". J. Biol. Chem. 280...
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