Edwin Goldmann

Edwin Goldmann
Born(1862-11-12)12 November 1862
Burgersdorp, Cape Colony
Died12 August 1913(1913-08-12) (aged 50)
Freiburg im Breisgau, Germany
Scientific career
Academic advisors
Paul Ehrlich

Edwin Goldmann (12 November 1862 – 12 August 1913) was a biomedical researcher and surgeon most famous for his contributions in first characterizing the blood–brain barrier.[1]

Discovery of the blood–brain barrier

Goldmann's mentor, Paul Ehrlich, was studying staining in his bacteriological studies by injecting aniline dyes in several species of animal. While most of the anatomy stained equally well, the brain tissue exhibited less staining in many species. Goldmann discovered that when the dye (namely, trypan blue) was injected directly into the central nervous system instead of into the other organs, the brain would stain equally well as other organs — but the stain would not travel to the rest of the body.

This suggested the presence of a compartmentalization between the cerebrospinal fluid and the vasculature of the rest of the body. This barrier was first hypothesized by a Berlin physician, Max Lewandowsky, in 1900 (prior to Goldmann's empirical evidence).[1]

Edwin Goldmann died from liver cancer in Freiburg on 13 August 1913.[2]

References

  1. ^ a b "The Late Professor Edwin Goldmann's Investigations on the Central Nervous System by Vital Staining". British Medical Journal. 2 (2753): 871–873. 4 October 1913. ISSN 0007-1447. PMC 2345891. PMID 20766814.
  2. ^ "Doctor Dies a Martyr". The Evening Sun. Berlin. 13 August 1913. p. 2. Retrieved 14 April 2020 – via Newspapers.com.
Flag of GermanyScientist icon Stub icon

This article about a German biologist is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.