DOKUMEN123.COM

Rowley; T. K. Woo; K. Fagnou (2006). "Catalytic Intermolecular Direct Arylation of Perfluorobenzenes". J. Am. Chem. Soc. 128 (27): 8754–8756. Bibcode:2006JAChS...

The Meerwein arylation is an organic reaction involving the addition of an aryl diazonium salt (ArN2X) to an electron-poor alkene usually supported by...

preparation of numerous pharmaceuticals. Industrial applications include α-arylation of carbonyl compounds (such as ketones, esters, amides, aldehydes) and...

new C–H functionalization reactions, especially in the areas of direct arylation and alkylation by palladium and ruthenium. CMD begins with a high valent...

(dimethylbenzene) The naphthyl group (C10H7−), which is derived from naphthalene Arylation is the process in which an aryl group is attached to a substituent. It...

+ H2 → 2 Ag + 2 CH3CO2H Silver acetate is a reagent for direct ortho-arylation (to install two adjacent substituents on an aromatic ring) of benzylamines...

reaction two arenes couple directly (sometimes called Friedel–Crafts arylation). In the Blanc chloromethylation a chloromethyl group is added to an arene...

H − C ≡ C − H {\displaystyle {\ce {H-C#C}}{\ce {-H}}} Acetylene H − C ≡ C − C | H H | − H {\displaystyle {\ce {H-C#C}}{-}{\ce {\overset {\displaystyle...

workup. Additionally, a one-pot magnesium–halogen exchange with subsequent arylation has been developed, showcasing the stability of the Weinreb–Nahm amide...

bismuth(V) reagent loses an aryl group and binds to oxygen. The subsequent arylation and elimination are asynchronous and concerted: Adjacent electron-pair...

meta-selective C–H arylation reaction on anilide derivatives. Despite the intrinsic ortho-/para- selectivity of the amido group, the arylation occurs exclusively...

Enantioenriched Benzylic Alcohols in a Single Flask: Catalytic Asymmetric Arylation of Aldehydes". Angewandte Chemie International Edition. 45 (25): 4175–4178...

Dominic; Monaco, Kevin; Wang, R.; Winter, Michael (1998). "New N- and O-Arylations with Phenylboronic acids and Cupric Acetate". Tetrahedron Lett. 39 (19):...

(HM) reaction is an organic reaction and a type of palladium catalysed arylation of olefins that uses arenediazonium salts as an alternative to aryl halides...

gold to the protein backbone. Trp arylation Multiple methods have been reported to achieve tryptophan C–H arylation, where diverse electrophiles such...

Meerwein–Ponndorf–Verley reduction, the Wagner–Meerwein rearrangement, the Meerwein arylation reaction, and Meerwein's salt. His father was the architect, Wilhelm Emil...

of an electrophile (e.g. alkyl or acyl halides). On the other hand, N-arylation is usually achieved by cross-coupling reactions with aryl halides using...

OLEDs as hole-transporters. Triphenylamine can be prepared by Ullmann arylation of diphenylamine. Triphenylamine has three aromatic groups directly linked...

activation, Larrosa has also published several research on decarboxylation and arylation reactions. Corday–Morgan Prize (2019) Blavatnik Awards (UK) Finalist (2019)...

Ryuzo; Teranishi, Shiichiro (1969). "Aromatic substitution of olefins. VI. Arylation of olefins with palladium(II) acetate". J. Am. Chem. Soc. 91 (25): 7166–9...

followed by a copper(II) chloride catalyzed arylation with furfural (essentially a modified Meerwein arylation). This then reacts with 1-aminohydantoin to...

array of reactions, including the arylation of ketones and esters, borylation of aryl chlorides, and the arylation of indoles. Many modified versions...

Intermolecular Enolate Heterocoupling (2008) Direct arylation of indoles (2009) Direct arylation of e-deficient heterocyles (2010) Nickel-Promoted Diene/Alkyne...

cause generation of reactive oxygen species (ROS) by redox cycling and arylation of thiols using its reactive 3-position. ROS generation explains various...

to give polyketones. Dppp can sometimes be used in palladium-catalyzed arylation under Heck reaction conditions to control regioselectivity. Birkholz (née...

4-triazoles (overview of recent methods) Virant, M.; Košmrlj, J. (2019). "Arylation of Click Triazoles with Diaryliodonium Salts". J. Org. Chem. 84 (21):...

groups such as nitro groups ortho or para to the halogen atom. For the arylation of amines with unactivated aryl halides, the Buchwald-Hartwig reaction...

signal.[clarification needed] Colletto et al. developed a regioselective β-arylation of benzo[b]thiophenes at room temperature with aryl iodides as coupling...

Lafrance, Marc; Fagnou, Keith (2006-12-27). "Palladium-catalyzed benzene arylation: incorporation of catalytic pivalic acid as a proton shuttle and a key...

maint: work parameter with ISBN (link) "Aniline synthesis by amination (Arylation)". Chisholm 1911, p. 48. McMurry, John E. (1992). Organic Chemistry (3rd ed...

pharmaceutical field. Typically, it is produced through three methods: an arylation reaction of benzothiophene; a coupling reaction between 2-benzothiophene...

oxidation routes, diaryl sulfoxides can be prepared by two Friedel–Crafts arylations of sulfur dioxide using an acid catalyst: 2 ArH + SO2 → Ar2SO + H2O Both...

Figure 2. Heck arylation catalyzed by the CNT supported palladium catalyst...

as a catalyst, either in the form of the metal or copper salts. Modern arylations use soluble copper catalysts. A traditional Goldberg reaction involves...

C6H5SC(S)OC2H5 + N2 C6H5SC(S)OC2H5 + H2O → C6H5SH + HOC(S)OC2H5 In the Meerwein arylation, benzenediazonium chloride reacts with compounds containing activated...

leading to a non-aromatic sulfoxide/sulfone: In palladium-catalysed C-H arylations, the N-oxide shifts the reactivity to reliably favor the 2-position, and...

dehydrogenation give carbazole: (C6H5)2NH + 0.5 O2 → (C6H4)2NH + H2O Arylation with iodobenzene gives triphenylamine. The Dische test uses diphenylamine...

Reaction Category RXNO ID Wikipedia Category 1 Heteroatom alkylation and arylation Category:Carbon-heteroatom bond forming reactions 2 Acylation and related...

611–614. Bibcode:1956JAChS..78..611R. doi:10.1021/ja01584a025. Modern Arylation Methods. Edited by Lutz Ackermann 2009 WILEY-VCH Verlag GmbH & Co. KGaA...

1021/jo00979a024. Mizoroki, Tsutomu; Mori, Kunio; Ozaki, Atsumu (1971). "Arylation of Olefin with Aryl Iodide Catalyzed by Palladium". Bull. Chem. Soc. Jpn...

Alkylation Alkyne trimerisation Alkyne metathesis Aminolysis Amination Arylation Barbier reaction Beta-hydride elimination Birch reduction Bönnemann cyclization...

g., Ullmann coupling, Suzuki–Miyaura reaction, or palladium-catalyzed arylation of arenes. Subsequent to the synthesis, the racemic biaryl is resolved...

formic acid to give 1-adamantanecarboxylic acid... ...and a Scholl-type arylation with benzene and acidic clay. Nitration of adamantane is a difficult reaction...

yield of about 45% to 1-phenylnaphthalene. The ruthenium(II)-catalyzed arylation of 1-tetralone using phenyl boronic acid neopentyl glycol ester gives...

Anders (1997). "Intramolecular Enantioselective Palladium-Catalyzed Heck Arylation of Cyclic Enamides". The Journal of Organic Chemistry. 62 (3): 595–602...

[P(CH2OH)4+]X− A variety of phosphonium salts can be prepared by alkylation and arylation of organophosphines: PR3 + R'X → [PR3R'+]X− Phosphoranes (σ5λ5) are formally...

DOI: 10.1021/ol302987h Asymmetric organocatalytic formal double-arylation of azomethines for the synthesis of highly enantiomerically enriched isoindolines...

of palladium hydroxide on carbon gave PC141452305 (5). The selective arylation with 4-bromo-2-fluoro-1-iodobenzene [105931-73-5] (6) in the presence...

research program primarily devoted to the development of novel "direct arylation" reactions which allow for the rapid synthesis of important building blocks...

be developed as a derivative of 1,3-oxazole or by stereo-controlled N-arylation of alpha-amino acids. Inavolisib has an oral bioavailability of 76%, which...

(2011). "Synthesis of 2-aryl Pyridines By Palladium-catalyzed Direct Arylation of Pyridine N-oxides". Org. Synth. 88: 22. doi:10.15227/orgsyn.088.0022...

this direct β-arylation of aldehydes led to related reactions for the β-functionalization of cyclic ketones. In particular, β-arylation of cyclic ketones...

1021/jo1010284 Yeung PY, Chung KH, Kwong FY. Palladium-catalyzed decarboxylative arylation of potassium cyanoacetate: Synthesis of α-diaryl nitriles from aryl halides...

biaryl syntheses, utilizing DMEDA as a catalyst to facilitate direct C−H arylation of unactivated benzene. In March 2013, he was awarded Senior Research...

especially benzyl derivatives and thioacetals. Thiophenols are produced by S-arylation or the replacement of diazonium leaving group with sulfhydryl anion (SH−):...

(mono-protected amino oxazoline) ligand allowed for C(sp3)–H functionalization via arylation of α-methyls, borylation of cyclobutyl carboxylic amides, and boronic...

product of much research, such as transfer hydrogenation and directed arylations. Panten, Johannes; Surburg, Horst (2016). "Flavors and Fragrances, 3....

also is used as a monoprotected version of acetylene. For example, after arylation at carbon, the acetone can be removed with base: HC2C(OH)Me2 + ArX + base...

1016/j.tetasy.2015.09.008. Cuny GD (2004-02-10). "Intramolecular ortho-Arylation of Phenols Utilized in the Synthesis of the Aporphine Alkaloids (.+-.)-Lirinidine...

(to fluorenone) to name just a few. Graebe–Ullmann synthesis Meerwein arylation Sandmeyer reaction Gomberg, M.; Bachmann, W. E. (1924). "The Synthesis...

absence of copper center. CuFe2O4 can also be applied for C-C cleavage α-arylation between acetylacetone with iodobenzene. The phenylacetone product was...

also refer to several chemical terms named after Hans Meerwein: Meerwein arylation Meerwein–Ponndorf–Verley reduction Meerwein's salt Wagner–Meerwein rearrangement...

Halogen transfer reaction with electron-deficient alkenes in the Meerwein arylation biaryl couplings Sandmeyer reactions addition to iminium ions addition...

Purines by a Combination of the Suzuki Cross-coupling, N-Arylation, and Direct C-H Arylation Reactions". J. Org. Chem. 73 (22): 9048–9054. doi:10.1021/jo8018126...

pages 5526–5548 Mizoroki, Tsutomu; Mori, Kunio; Ozaki, Atsumu (1971). "Arylation of Olefin with Aryl Iodide Catalyzed by Palladium". Bulletin of the Chemical...

Schley, Nathan D.; Fu, Gregory C. (2014-11-26). "Nickel-Catalyzed Negishi Arylations of Propargylic Bromides: A Mechanistic Investigation". Journal of the...

Syntheses, Karl Anker (2014). "Enantioselective Organocatalytic α-Arylation of Aldehydes". Organic Syntheses. 91: 175–184. doi:10.15227/orgsyn.091...

by a two-step, one-pot procedure beginning with a Friedel-Crafts-like arylation, with trichlorocyclopropenium as an intermediate prepared in situ: C3Cl4...

PMID 844529.. ^ Moro, A. V.; Cardoso, F. S. P.; Correia, C. R. D. (2008). "Heck arylation of styrenes with arenediazonium salts: Short, efficient, and stereoselective...

Deborshee Das and Osvaldo Gutierrez. "Fe-catalyzed Fluoroalkyl(hetero)arylation of Vinyl Azaarenes: Rapid and Modular Synthesis of Unsymmetrical 1...

"Palladium-catalyzed carbon-sulfur or carbon-phosphorus bond metathesis by reversible arylation". Science. 356 (6342): 1059–1063. Bibcode:2017Sci...356.1059L. doi:10...

J.; Buchwald, Stephen L. (2002). "A General and Mild Copper-Catalyzed Arylation of Diethyl Malonate". Organic Letters. 4 (2): 269–272. doi:10.1021/ol017038g...

Efficient Copper Catalyst for the Amidation of Aryl Halides and theN-Arylation of Nitrogen Heterocycles". Journal of the American Chemical Society. 123...

Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds". The Journal of Organic Chemistry...

For example, it mediates the C–H bond arylation of arenes with arylboronic acids and is used in the arylation of indoles with triphenylbismuth bis-trifluoroacetate...

addition step, along with being easily removed when needed in further steps. Arylation at C3 gave intermediate 3, with the correct direction of optical rotation...

requires a strong (radical) leaving group. One example is the Meerwein arylation. A radical addition which leaves an unsaturated product can undergo radical...

Seyferth, Dietmar; Hallgren, John E.; Spohn, Ralph J. (1970). "The C-arylation and alkylation of methylidynetricobalt nonacarbonyls by organomercury...

(2011). "Synthesis of 2-aryl Pyridines By Palladium-catalyzed Direct Arylation of Pyridine N-oxides". Org. Synth. 88: 22. doi:10.15227/orgsyn.088.0022...

Fricke, Christoph; Schoenebeck, Franziska (2020). "Modular and Selective Arylation of Aryl Germanes (C−GeEt 3 ) over C−Bpin, C−SiR 3 and Halogens Enabled...

Grignard reagents provides a route to tertiary alcohols. Alkylation and arylation can be achieved using malonate anions and arenes/AlCl3, respectively....

Qi-Sheng; Ye, Mengchun (2016-10-11). "Ligand-Accelerated Direct C−H Arylation of BINOL: A Rapid One-Step Synthesis of Racemic 3,3′-Diaryl BINOLs". Angewandte...

doi:10.1007/128_073. ISBN 978-3-540-68097-0. Stamos, Ioannis K. (1986). "Arylation of α-phosphoryl sulfides via their pummerer rearrangement intermediates...

chemistry, in one-pot reactions, to affect the direct regioselective arylation, alkenylation, cyanation and further functionalisation of C-H positions...

Wenbo, H. Liu (2024). "Unified ionic and radical C-4 alkylation and arylation of pyridines". Chemical Science. 15 (31): 12442–12450. doi:10.1039/d4sc03739a...

Klára; Zbořil, Radek; Otyepka, Michal (2017). "High-Yield Alkylation and Arylation of Graphene via Grignard Reaction with Fluorographene". Chemistry of Materials...

decarboxylation of phenylalanine. Benzyl cyanides can also be prepared by arylation of silyl-substituted acetonitrile. Benzyl cyanide undergoes many reactions...

of functionalized quinolines via Ugi and Pd-catalyzed intramolecular arylation reactions". Journal of Combinatorial Chemistry. 8 (5): 696–704. doi:10...

Motherwell, William B.; Papoula, M. Teresa Barros (1980). "Comparative arylation reactions with pentaphenylbismuth and with triphenylbismuth carbonate"...

(2009), "Efficient synthesis of 3-arylphthalides using palladium-catalyzed arylation of aldehydes with organoboronic acids", Journal of Organic Chemistry,...

Borilovic, Ivana; Aromı́, Guillem; Hevia, Eva (2015-06-08). "Zincate-Mediated Arylation Reactions of Acridine: Pre- and Postarylation Structural Insights" (PDF)...

tetrachloride is the gateway compound for high valent organotellurium compounds. Arylation gives, depending on conditions, Te(C6H4R)2Cl2, [Te(C6H4R)5]−, [Te(C6H4R)6]2−...

used in this context. Examples of arylation and acylation reactions are shown below. Although intermolecular arylations using nitrile anions result in modest...

"Mechanism of Ni-Catalyzed Photochemical Halogen Atom-Mediated C(sp3)-H Arylation" J. Am. Chem. Soc. 2024, 146, 15331-15344. Jennings, Penny (Jun 30, 2021)...

depurination as caused by the adducts is in generating mutation. Alkylation and arylation of bases can cause errors in replication. Some alkylating agents such...

2021). "P-chirogenic phosphorus compounds by stereoselective Pd-catalysed arylation of phosphoramidites". Nature Catalysis. 5: 10–19. doi:10.1038/s41929-021-00697-9...

reactions at the ortho position. These include alkylation from alkyl halides, arylation from aryl bromides, amination from benzyloxyamines, acylation from anhydrides...

P,N-Ligand for Pd-Catalyzed Ammonia Arylation: Coupling of Deactivated Aryl Chlorides, Chemoselective Arylations, and Room Temperature Reactions." R....

Herzon, Seth B. (2012-09-07). "Room Temperature, Palladium-Mediated P –Arylation of Secondary Phosphine Oxides". Organic Letters. 14 (17): 4370–4373. doi:10...

Aihara, Yoshinori; Chatani, Naoto (May 2015). "ChemInform Abstract: Direct Arylation of C(sp3)-H Bonds in Aliphatic Amides with Diaryliodonium Salts in the...

"Palladium-catalyzed synthesis of N-aryl-2-benzylindolines via tandem arylation of 2-allylaniline: control of selectivity through in situ catalyst modification"...

refer to several chemical reactions named after Hans Meerwein: Meerwein arylation Meerwein–Ponndorf–Verley reduction Wagner–Meerwein rearrangement This...

"Synthesis of pentabromopseudilin and other arylpyrrole derivatives via Heck arylations". Tetrahedron Letters. 53 (13): 1660–1663. doi:10.1016/j.tetlet.2012.01...

Arthur C. Cope Scholar Award Schomaker JM; Delia TJ (1 October 2001). "Arylation of halogenated pyrimidines via a Suzuki coupling reaction". The Journal...

aldehydes using unactivated alkyl iodides in water The Barbier–Grignard-type arylation of aldehydes using unactivated aryl iodides in water Silver-Catalyzed...

molecular electronics as well as some dyes. Triarylamines can be produced by arylation of diarylamides with aryl iodides: Ar2NLi + Ar'I → Ar2Ar'N + LiI Buchwald-Hartwig...

indole had regioselectivity issues. Fagnou's group showed that direct C-H arylation of an indole is possible using palladium catalysis with a copper oxidant...

deactivation however. The precatalyst are prepared by alkylation and arylation of the phosphinimide complexes is possible through alkyllithium or Grignard...

supply-risk transition metals. Examples include metal-free alkylation and arylation of benzothiophenes, metal-free synthesis of benzothiophenes by twofold...

T.; Lloyd-Jones, G. C.; Russell, C. A. (2012). "Gold-Catalyzed Direct Arylation" (PDF). Science. 337 (6102): 1644–1648. Bibcode:2012Sci...337.1644B. doi:10...

de Mendoza, P.; Echavarren, A. M. (20 July 2007). "Palladium catalyzed arylation for the synthesis of polyarenes". Organic and Biomolecular Chemistry....

Stephen G. (2024). "Synthesis of Secondary Benzylic Alcohols by Reductive Arylation of Aldehydes: α-Phenyl-6-quinolinemethanol". Organic Syntheses. 101: 1–20...

tert-butoxyapatite by incorporating basic species F-/tBuO- in apatite for N-arylation of imidazoles with chloroarenes and fluoroarenes for the first time. She...

PMID 26575368. Ackerman, Lutz (2009). Ackermann, Lutz (ed.). Modern Arylation Methods. Verlag: Wiley-VCH. doi:10.1002/9783527627325. ISBN 9783527319374...

Reisman, Sarah E. (2013-04-03). "Copper-Catalyzed Diastereoselective Arylation of Tryptophan Derivatives: Total Synthesis of (+)-Naseseazines A and B"...

(2008). "Multifaceted Palladium Catalysts Towards the Tandem Diboration–Arylation Reactions of Alkenes". Chemistry – A European Journal. 14 (34): 10648–10655...

Enantioenriched Benzylic Alcohols in a Single Flask: Catalytic Asymmetric Arylation of Aldehydes". Angewandte Chemie International Edition. 45 (25): 4175–4178...

PMID 29698504. "MycetOS – DNDi". 31 December 2017. Park, SJ (2002). "Oxidative Arylation of Isochroman". Journal of Organic Chemistry. 77 (2): 949–955. doi:10...

Aryl Chlorides with Organochlorosilanes: Highly Effective Methods for Arylation or Alkenylation of Aryl Chlorides", The Journal of Organic Chemistry,...

Marc (2004-10-29). "Highly Efficient and Mild Copper-Catalyzed N- and C-Arylations with Aryl Bromides and Iodides". Chemistry – A European Journal. 10 (22):...

Functionalization of PyridineN-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes". Journal of the American Chemical Society. 130...

Jiang, Yuyang; Zhao, Yufen (2007-01-01). "CuBr/rac-BINOL-Catalyzed N-Arylations of Aliphatic Amines at Room Temperature". The Journal of Organic Chemistry...

2012 while working with Matthew J. Gaunt on strategies for asymmetric arylation. In 2012, Motion moved to the University of Sydney in Australia to work...

 100. LCCN 65-27436. Robert P. Kozyrod, John T. Pinhey (1984). "The C-Arylation of β-Dicarbonyl Compounds". Organic Syntheses. 62: 24. doi:10.15227/orgsyn...

"Exogenous-Base-Free Palladacycle-Catalyzed Highly Enantioselective Arylation of Imines with Arylboroxines". Angewandte Chemie International Edition...

recently, these ligands were applied to the enantioselective decarboxylative arylation of α-amino acids by MacMillan and Fu. Semicorrins and CN-BOX are L,X-type...

Sommai; Satoh, Tetsuya; Nomura, Masakatsu (2000). "Palladium-Catalyzed Arylation of Cyclopentadienes". Chemistry - A European Journal. 6 (18): 3426–3433...

product post-reaction. Copper ferrite has been reported as a heterocycle arylation catalyst and can be similarly separated from the reaction with a magnet...

2021). "P-chirogenic phosphorus compounds by stereoselective Pd-catalysed arylation of phosphoramidites". Nature Catalysis. 5: 10–19. doi:10.1038/s41929-021-00697-9...

(1996). "Characterization of Reactive Intermediates in Palladium-Catalyzed Arylation of Methyl Acrylate (Heck Reaction)". Angewandte Chemie International Edition...

ISBN 0-471-69754-0. J.M. McClure, Samuel J. Danishefsky: "A novel Heck arylation reaction: rapid access to congeners of FR 900482", in: J. Am. Chem. Soc...

strength of the ligand. CAAC-6 was shown to be more effective in the α-arylation of ketones with aryl chlorides than the analogous CAAC-5. Compared to...

2022). "P-chirogenic phosphorus compounds by stereoselective Pd-catalysed arylation of phosphoramidites". Nature Catalysis. 5 (1): 10–19. doi:10.1038/s41929-021-00697-9...

D. R.; Gasser, Valentina C. M.; Morandi, Bill (2021-04-08). "Shuttle arylation by Rh(I) catalyzed reversible carbon–carbon bond activation of unstrained...

13 and (+)-Himgaline. Büchner–Curtius–Schlotterbeck reaction Meerwein arylation Holmquist, Christopher R.; Roskamp, Eric J. (1989-07-01). "A selective...

indenocorannulenes synthesized by iterative microwave-assisted intramolecular arylations". Journal of the American Chemical Society. 131 (30): 10537–10545. doi:10...

McDougall monoprotection McFadyen–Stevens reaction McMurry reaction Meerwein arylation Meerwein–Ponndorf–Verley reduction Meisenheimer rearrangement Meissenheimer...

Teranishi, Shiichiro (1969-12-01). "Aromatic substitution of olefins. VI. Arylation of olefins with palladium(II) acetate". Journal of the American Chemical...

functionality. In the presence of diaryliodonium salts, enolates undergo α-arylation. Bulky diaryliodoniums react more slowly, and enolate homocoupling (see...

catalysis. Rhodium(I) complexes of CDCs have been used in diene hydro-arylation, alkylation, and amination while CDC nickel complexes have allowed for...

Jin-Ho (15 May 1998). "The relative importance of oxidative stress versus arylation in the mechanism of quinone-induced cytotoxicity to platelets". Chemico-Biological...

PMID 22468962.. Stolley, RM; Guo, W; Louie, J (2012). "Palladium-catalyzed arylation of cyanamides". Org Lett. 14: 322–5. doi:10.1021/ol203069p. PMC 4113087...

"Sequential Hydrocarbon Functionalization: Allylic C-H Oxidation/Vinylic C-H Arylation". J. Am. Chem. Soc. 128 (47): 15076–15077. doi:10.1021/ja066563d. PMID 17117844...

hdl:2445/164459. S2CID 202885438. Ackermann, Lutz (2007). "Catalytic Arylations with Challenging Substrates: From Air-Stable HASPO Preligands to Indole...