Single-Copy-Gen

Als single-copy-Gen bezeichnet man Gene, die nur in einer einzigen Kopie im gesamten Genom vorkommen.[1]

Beispiele für single-copy-Gene:

  • Das PrP-Protein codierende Gen namens PRNP, welches auf dem kurzen Seitenarm des 20. Chromosoms des Menschen lokalisiert ist und etwa 750 Basenpaare umfasst.
  • Die b-Actin-Sequenz, welche in vielen Organismen hoch konserviert ist und so zur Differenzierung von Genomen verschiedener Organismen verwendet werden kann.

Einzelnachweise

  1. ↑ D. M. Coen: Quantitation of rare DNAs by PCR. In: Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 10Mai 2001, S. Unit 10.21, ISSN 1934-368X. doi:10.1002/0471142735.im1021s24. PMID 18432686.

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