DISC2

DISC2
Identifikatori
AliasiDISC2
Vanjski ID-jeviOMIM: 606271 GeneCards: DISC2
Ortolozi
VrsteČovjekMiš
Entrez

27184

n/a

Ensembl

ENSG00000274121

n/a

UniProt

n
a

n/a

RefSeq (mRNK)

n/a

n/a

RefSeq (bjelančevina)

n/a

n/a

Lokacija (UCSC)n/an/a
PubMed pretraga[1]n/a
Wikipodaci
Pogledaj/uredi – čovjek

Protein nekodirajuća shizofrenijski poremećena RNK 2, znana i kao DISC2 – u molekulskoj biologiji – je molekula dugolančane nekodirajuće RNK. Kod ljudi proizvodi molekule RNK kodiranee genom DISC2 sa hromosoma 1, na tački prekida povezanom sa hromosomskom translokacijom pronađenom u shizofreničara.[2]

Ona je antisensna genu DISC1 i može regulisati ekspresiju DISC1.[2][3] DISC2 također može doprinijeti drugim psihijatrijskim poremećajima.[3][4]

Također pogledajte

Reference

  1. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. ^ a b Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, Devon RS, St Clair DM, Muir WJ, Blackwood DH, Porteous DJ (maj 2000). "Disruption of two novel genes by a translocation co-segregating with schizophrenia". Human Molecular Genetics. 9 (9): 1415–1423. doi:10.1093/hmg/9.9.1415. PMID 10814723.
  3. ^ a b Millar JK, James R, Brandon NJ, Thomson PA (2004). "DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness". Annals of Medicine. 36 (5): 367–378. doi:10.1080/07853890410033603. PMID 15478311. S2CID 36081296.
  4. ^ Hodgkinson CA, Goldman D, Jaeger J, Persaud S, Kane JM, Lipsky RH, Malhotra AK (Nov 2004). "Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder". American Journal of Human Genetics. 75 (5): 862–872. doi:10.1086/425586. PMC 1182115. PMID 15386212.

Dopunska literatura

Vanjski linkovi

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.