Akrosom

Ulazak spermatozoioda u jajnu ćeliju praćen akrosomskom reakcijom
Ljudski spermatozoid

Akrosom je organela koja se nalazi u prednjem dijelu spermatozoida i služi za njegovu interakciju s jajnom ćelijom prilikom oplodnje. Nastaje od Golgijevog aparata tokom spermiogeneze kada se spermatide transformiraju u spermatozoide.[1]

Akrosom sadrži hidrolitičke enzime kao što su:

Prilikom oplodnje, kada spermatozoid akrosomom dodirne primarnu opnu jajne ćelije dolazi do akrosomske reakcije u toku koje se ovi enzimi izlučuju procesom egzocitoze.

Akrosomskom reakcijom postižu se važne funkcije koje određuju sposobnost spermatozoida da oplodi jajnu ćeliju:

  • oslobađanje hidrolitičkih enzima pomoću kojih spermatozoid prodire u jajnu ćeliju;
  • promjena omotača postakrozomskog predjela na kome su receptori odgovorni za interakciju spermatozoida i jajne ćelije.[2][3]

Reference

  1. ^ Hermann Behre; Eberhard Nieschlag (2000). Andrology : Male Reproductive Health and Dysfunction. Berlin: Springer. str. 155. ISBN 3-540-67224-9.
  2. ^ Miyazaki R, Fukuda M, Takeuchi H, Itoh S, Takada M (1990). "Flow cytometry to evaluate acrosome-reacted sperm". Arch. Androl. 25 (3): 243–51. doi:10.3109/01485019008987613. PMID 2285347.CS1 održavanje: upotreba parametra authors (link)
  3. ^ Carver-Ward JA, Moran-Verbeek IM, Hollanders JM (februar 1997). "Comparative flow cytometric analysis of the human sperm acrosome reaction using CD46 antibody and lectins". J. Assist. Reprod. Genet. 14 (2): 111–9. doi:10.1007/bf02765780. PMC 3454831. PMID 9048242.CS1 održavanje: upotreba parametra authors (link)

Vanjski linkovi

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Logo Commonsa
Acrosome na Wikimedia Commonsu.

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