The station carries syndicated national radio talk shows including "The Rush Limbaugh Show", "The Sean Hannity Show", "The Dave Ramsey Show", "Glenn Beck Program", and other national news/talk programs. Local programming includes a morning news program called "Auburn/Opelika This Morning with Bob Wooddy" and a weekly news recap show called "Auburn/Opelika This Week with Chuck Wacker".
WANI simulcasts all of its broadcasting on W254AY 98.7 FM via WGZZ-HD2.