Crane was born in Elizabethtown. He served as sheriff of Essex County and was elected as a member of its town committee in 1750. He was also a judge of the court of common pleas. From 1766 to 1773, he was a member of the colony's general assembly from 1766 to 1773 and served as speaker in 1771. He was also mayor of Elizabethtown before he became a member of the Continental Congress. Until his death in 1780, Crane held several public offices in New Jersey.
William Crane, son; born 1748 in Elizabethtown, served as major of an Essex County, New Jersey regiment. Fought with Richard Montgomery in the Battle of Quebec, received a leg wound that required amputation years later. Promoted to brigadier general in the New Jersey militia after the war.