Kyabram was a foundation club in the Goulburn Valley Football League (GVFL) and has been one of the most dominant. Only the Shepparton Football Club have won more premierships.
The club had a successful era the 1920s, when they won five GVFL premierships, including the Kyabram Reserves winning the senior football premiership in the Northern Goulburn Football Association in 1929.
The club has produced many VFL/AFL footballers, including Ross Dillon, Garry Lyon, Kayne Pettifer, Nick Holman and Brett Deledio. Kyabram's Chris Stuhldreier won the GVFL goal-kicking every season from 1991 to 1994, including a record setting 164 goals in 1993.
Between 2016 and 2018 the club won an astounding 62 consecutive wins. The sequence stopped at the 2018 Grand Final. The club was undefeated in 2019.