While it was still a construction permit, the station was assigned the call letters KBHD on July 17, 1998. On September 18, 1998, the station changed its call sign to KKPN.[5]
The station signed on the air in 1999; 25 years ago (1999).[6] The call sign changed again on March 26, 2001, to the current KPUS. The call letters stood for the station's moniker and mascot, "The OctoPUS."
On March 26, 2020, ICA Radio relaunched Classic Rock 104.5 as "104.5 The Eagle, Corpus Christi's ONLY Classic Rock Station."[7]