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(1890–1967), who was a 1946 Nobel Prize winner, coined the terms amorph, hypomorph, hypermorph, antimorph and neomorph to classify mutations based on their...

Aguirre GK, Van Deerlin VM, Lee EB (November 2020). "Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau". Science. 370 (6519) eaay8826...

Hydrogen bond Hydroxyapatite Hypermorph Hyperploid Hypervariable region Hypomorph Hypoploid Hypostatic gene Ichthyosis Identical twin Identity by descent...

PMID 12142353. Darwich NF, Phan JM, et al. (2020). "Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau". Science. 370 (6519) eaay8826...

PMID 18845250. Darwich, N.F., Phan J.M.; et al. (2020). "Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau". Science. 370 (6519) eaay8826...

hypotonic environments may be at risk of bursting due to the sudden inflow. hypomorph A mutant allele that permits a subnormal expression of the gene's normal...

expression of parent allele Amorph Dysfunctional, with null expression Hypomorph Reduced or partially reduced gene activity Hypermorph Increased or partially...

in the duration of ontogenetic development over evolutionary history. hypomorph A mutant allele that permits a subnormal expression of the gene's normal...

survival. Loss of Crim1 function as demonstrated by the Crim1 KST264 hypomorph mice resulted in onset of chronic kidney disease with accompanying pathology...

L, Dong H, Dalton TP, Nebert DW (July 2011). "Generation of a Slc39a8 hypomorph mouse: markedly decreased ZIP8 Zn2+/(HCO3−)2 transporter expression"....

Carli JF, O'Day DR, Wang L, Leduc CA, Lanzano P, et al. (May 2014). "Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased...

Yamashita YM, Pallanck LJ, Malik HS (August 2016). "A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila...

Papatriantafyllou JD, Changolkar L, et al. (November 2020). "Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau". Science. 370 (6519) eaay8826...

powerful collections can be used to probe any genetic investigation. For hypomorphs, this allows the incremental reduction of gene function as opposed to...

models of underexpression and overexpression were also generated. The hypomorph Drosophila model revealed molecular function of PQBP1 in learning acquisition...

with human obesity, and promote the expression of RPGRIP1L. RPGRIP1L hypomorphism in mice results in obesity, suggesting an important role of CUX1 in body...

D, O'Rahilly S, Carel JC, Barroso I, O'Driscoll M, Semple R (2014). "Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance"...

reduce therapeutic response to acetylcholine inhibitors because of its hypomorphism. CHRFAM7A is expressed rapidly in human leukocytes and regulated immune...

Michael; Egli, Dieter; Doherty, Daniel A.; Leibel, Rudolph L. (May 2014). "Hypomorphism for RPGRIP1L, a Ciliary Gene Vicinal to the FTO Locus, Causes Increased...