Low was admitted to the bar, and practiced law in partnership with Niven.
Low was a Judge and Surrogate of the Sullivan County Court from 1857 to 1861.
He was a member of the New York State Senate (9th D.) in 1862 and 1863. In November 1863, Low ran for re-election, but his former law partner Niven was declared elected. Low contested Niven's election, and was seated in the State Senate for the 88th Session on January 17, 1865. He was re-elected in 1865, and continued in the Senate in 1866 and 1867. Afterwards he resumed his law practice in Middletown, Orange County, New York.