GSC may refer to:

• Game Show Central, an American TV network
• Global Security Challenge, a business competition
• Golden Screen Cinemas, in Malaysia
• Golden Star Resources, a Canadian gold mining company
• Good Smile Company, a Japanese manufacturer of hobby products
• GSC Enterprises, Inc., an American retailer and financial services company
• GSC Systems, a Canadian propeller manufacturer

• Gainesville State College, now a campus of the University of North Georgia, in Oakwood, Georgia, United States
• Glasgow Science Centre, in Scotland
• Glassboro State College, now Rowan University, in Glassboro, New Jersey, United States
• Glenville State College, now Glenville State University, in Glenville, West Virginia, United States
• Global Studies Consortium, an international academic association
• Government Saadat College, in Karatia, Tangail, Bangladesh
• Government Science College (disambiguation)
• Granite State College, in New Hampshire, United States
• Greensboro Science Center, in North Carolina, United States

• Game Show Congress, a conference series
• Granite State Challenge, an American quizbowl television show
• The Great Space Coaster, an American children's television show
• Gunsmith Cats, a Japanese seinen manga
• GSC Game World, a Ukrainian video game developer
• Pokémon Gold, Silver and Pokémon Crystal

• Air Force Global Strike Command, a major command of the United States Air Force
• General Service Corps, of the British Army
• Geological Survey of Canada

• GSC (gene), encoding the goosecoid protein
• Global Standards Collaboration, in telecoms
• Genomic Standards Consortium
• Group switching centre, a former British telephone exchange
• GSC bus, a computer bus
• Guangzhou Science City, in Guangdong, China
• Guiana Space Centre, in French Guiana
• Guide Star Catalog, an astronomical catalogue
• Google Search Console, a webmasters' tool

• Game score, a baseball statistic
• Gezira Sporting Club, largest multi-sport facility in Egypt
• Ghana Super Cup, a football competition
• Girls' Sports Club, a women's sports club in Singapore 1929-1996
• Glenmore Sailing Club, in Calgary, Alberta, Canada
• Goslarer SC 08, a German football club
• Gulf South Conference, a college athletic conference in the southeastern United States

• Gascon language, spoken in France
• General Santos City, a city in the Philippines
• Glenwood Springs station, a railway station in Colorado, United States
• Greater Sylhet Development and Welfare Council in UK, a British charity
• Green Schools Campaign, a renewable energy campaign in Malaysia
• Guided Self-Change
• Girl Scout Cookies
• Gulf Stream Council, of the Boy Scouts of America

This disambiguation page lists articles associated with the title GSC.
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