Ekpo is a surname and given name. Notable people with the name include:
Surname:
- Akpan Hogan Ekpo (born 1954), Nigerian economist and professor
- Comfort Ekpo (born 1954), Nigerian Vice Chancellor at the University of Uyo
- Efioanwan Ekpo (born 1984), Nigerian female footballer
- Emmanuel Ekpo (born 1987), Nigerian footballer
- Felix Ekpo (born 1981), Nigerian weightlifter competing in the 77 kg category
- Florence Ekpo-Umoh (born 1977), Nigerian-German sprinter who specializes in the 400 metres
- Friday Ekpo (born 1969), Nigerian footballer
- Isaac Ekpo (born 1982), Nigerian boxer
- Margaret Ekpo (1914–2006), Nigerian women's rights activist
- Mfon Ekpo (born 1982), Nigerian entrepreneur and author
- Moses Ekpo, Nigerian politician, Deputy Governor of Akwa Ibom State
Given name:
- Bassey Ekpo Bassey (born 1949), Nigerian journalist, politician and traditional ruler of the Efik people of the Akwa Akpa kingdom
- Ekpo Eyo (1931–2011), Nigerian scholar mostly known for his work on archeology of Nigeria
- Ekpo Una Owo Nta, Nigerian lawyer and Chairman of the Independent Corrupt Practices and Other Related Offences Commission
See also
