D'Agostino grew up in Longmeadow, Massachusetts and played high school soccer at the Loomis Chaffee School where she scored 76 goals with 44 assists in 65 games. She was named a Parade All-American in 2007 and was twice named a NSCAA High School All-American. Following the 2006–2007 season, she was named Connecticut Player of the Year. While on the team, the Loomis Chaffee School won three consecutive Class A New England Championship titles and had two completely undefeated seasons. From 2002 to 2007, D'Agostino was selected for the U-14 and 17 National Team Pools and was a Region I ODP member.[2]
Penn State University
D'Agostino attended Pennsylvania State University her freshman year where she played in 23 games (including nine starts) and recorded one assist.[2] After transferring to Wake Forest University, D'Agostino was named to the Wake Forest Nike Tournament All-Tournament Team, earned ACC Player of the Week honors (9/16) and was named Soccer America National Team of the Week (9/16) during her sophomore year. During her senior year, Bianca started all 24 games, totalling two goals and nine assists and was named co-captain of the squad. She was also named to ACC/SEC Challenge All-Tournament Team.[2]
After the WPS suspended operations in early 2012, D'Agostino signed with the Boston Breakers in the Women's Premier Soccer League Elite in May of the same year.[5] She played in 13 matches for the team and scored one goal during the season.[6]
The following year, a new professional league, the National Women's Soccer League was established and D'Agostino was signed by the Breakers in the NWSL Supplemental Draft. She was the team's third pick, 27th overall.[7] On April 9, 2013, Boston Breakers announced that D'Agostino had sustained a partially torn ACL and would miss a portion of the season.[8] She returned for the 2014 National Women's Soccer League season making 16 appearances including six starts.[6]
On September 16, 2014, D'Agostino announced her retirement from professional soccer.[6]