Ananain

Ananain
Identifiers
EC no.3.4.22.31
CAS no.119129-70-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Ananain (EC 3.4.22.31, stem bromelain, fruit bromelain) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Best reported small molecule substrate Bz-Phe-Val-Arg-NHMec

This enzyme is isolated from stem of pineapple plant, Ananas comosus.

References

  1. ^ Rowan AD, Buttle DJ, Barrett AJ (November 1988). "Ananain: a novel cysteine proteinase found in pineapple stem". Archives of Biochemistry and Biophysics. 267 (1): 262–70. doi:10.1016/0003-9861(88)90031-8. PMID 3196029.
  2. ^ Rowan AD, Buttle DJ, Barrett AJ (March 1990). "The cysteine proteinases of the pineapple plant". The Biochemical Journal. 266 (3): 869–75. PMC 1131219. PMID 2327970.

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