Ashleigh Barty and Jennifer Brady defeated Desirae Krawczyk and Bethanie Mattek-Sands in the final, 6–4, 5–7, [10–5], to win the doubles tennis title at the 2021 Stuttgart Open. By winning her 12th career WTA Tour doubles title, Barty became the first player since Lindsay Davenport in 2001 to sweep both tournaments in Stuttgart. This was also Brady's first career WTA Tour doubles title.[1]
Bold denotes the mandatory tournaments (WTA 1000) † – Tournaments are affected by the COVID-19 pandemic * – Tournaments are introduced due to the impact of the COVID-19 pandemic