Pete Sampras defeated Andre Agassi in the final, 6–4, 6–3, 6–2 to win the men's singles tennis title at the 1990 US Open. It was his first major title, and the first of a then-record 14 men's singles major titles overall.
Boris Becker was the defending champion, but lost to Agassi in the semifinals.
Sampras defeated Ivan Lendl in the quarterfinals, ending Lendl's record streak of eight consecutive men's finals appearances at the US Open.
Seeds
The seeded players are listed below. Pete Sampras is the champion; others show the round in which they were eliminated.