Michael J. Behe ( BEE -hee ; lahir 18 Januari 1952) adalah seorang ahli biokimia , pengarang dan pendukung intelligent design (ID) yang berasal dari Amerika Serikat . Ia menjabat sebagai profesor biokimia pada Lehigh University di Pennsylvania dan seorang senior fellow Center for Science and Culture pada Discovery Institute . Behe paling terkenal karena argumennya mengenai irreducible complexity (IC; "kerumitan tak tersederhanakan "), yang menyatakan bahwa sejumlah struktur biokimia terlalu kompleks untuk dijelaskan dengan mekanisme evolusi yang diketahui saat ini dan karenanya kemungkinan besar adalah hasil dari intelligent design ("perancangan cerdas "). Behe memberikan kesaksian ahli pada beberapa kasus pengadilan yang berhubungan dengan intelligent design , termasuk kasus pengadilan Kitzmiller v. Dover Area School District yang menghasilkan keputusan bahwa intelligent design bersifat agamawi.[ 2]
Publikasi
Buku
Behe, Michael J. (1996). Darwin's Black Box: The Biochemical Challenge to Evolution . New York: Free Press . ISBN 0-684-82754-9 . LCCN 96000695 . OCLC 34150540 .
——; Dembski, William A. ; Meyer, Stephen C. (2000). Science and Evidence for Design in the Universe: Papers Presented at a Conference Sponsored by the Wethersfield Institute, New York City, September 25, 1999 . Proceedings of the Wethersfield Institute. 9 . San Francisco, CA: Ignatius Press . ISBN 0-89870-809-5 . LCCN 00102374 . OCLC 45720008 .
—— (2003). "Design in the Details: The Origin of Biomolecular Machines". Dalam Campbell, John Angus ; Meyer, Stephen C. Darwinism, Design and Public Education . Rhetoric and Public Affairs Series. East Lansing, MI: Michigan State University Press . hlm. 287–302. ISBN 0-87013-670-4 . LCCN 2003020507 . OCLC 53145654 .
—— (2003). "The modern intelligent design hypothesis: breaking rules". Dalam Manson, Neal A. God and Design: The Teleological Argument and Modern Science . London; New York: Routledge . hlm. 277 –291. ISBN 0-415-26344-1 . LCCN 2002027548 . OCLC 50447710 .
—— (2004). "Irreducible Complexity: Obstacle to Darwinian Evolution". Dalam Dembski, William A.; Ruse, Michael . Debating Design: From Darwin to DNA . New York: Cambridge University Press. hlm. 352 –370. ISBN 0-521-82949-6 . LCCN 2004047363 . OCLC 54826160 . "Papers from a conference, entitled Design and its Critics, held at Concordia University, Mequon, Wis., June 22–24, 2000."
——; Singh, Thoudam Damodara (2005). God, Intelligent Design & Fine-Tuning: A Discussion Between Michael J. Behe and T.D. Singh . Kolkata, West Bengal: Bhaktivedanta Institute. ISBN 81-89635-01-8 . LCCN 2006554901 . OCLC 70631564 .
—— (2007). The Edge of Evolution: The Search for the Limits of Darwinism . New York: Free Press. ISBN 0-7432-9620-6 . LCCN 2007298379 . OCLC 136958644 .
—— (2013). "Getting There First: An Evolutionary Rate Advantage for Adaptive Loss-of-Function Mutations". Dalam Marks II, Robert J. ; Behe, Michael J.; Dembski, William A.; Gordon, Bruce L. ; Sanford, John C. Biological Information--New Perspectives: Proceedings of a Symposium Held May 31, 2011 Through June 3, 2011 at Cornell University . Hackensack, NJ: World Scientific Publishing Co. hlm. 450–473. ISBN 978-981-4508-71-1 . LCCN 2013016707 . OCLC 858441131 .
Artikel Jurnal
Struktur DNA
Behe, Michael J.; Felsenfeld, Gary; Szu, Shousun Chen; Charney, Elliot (February 1985). "Temperature-dependent conformational transitions in poly(dG-dC) and poly(dG-m5 dC)" . Biopolymers . New York: Wiley InterScience . 24 (2): 289–300. doi :10.1002/bip.360240202 . ISSN 0006-3525 . PMID 3978220 .
—— (March 1986). "Vacuum UV CD of the low-salt Z-forms of poly(rG-dC).poly(rG-dC), and poly(dG-m5 dC).poly(dG-m5 dC)" . Biopolymers . New York: Wiley InterScience. 25 (3): 519–523. doi :10.1002/bip.360250310 . ISSN 0006-3525 . PMID 3754471 .
—— (December 1987). "The DNA sequence of the human β-globin region is strongly biased in favor of long strings of contiguous purine or pyrimidine residues". Biochemistry . Washington, D.C.: American Chemical Society . 26 (24): 7870–7875. doi :10.1021/bi00398a050 . ISSN 0006-2960 . PMID 3427110 .
——; Beasty, Anne M. (1991). "Co-polymer tracts in eukaryotic, prokaryotic, and organellar DNA". DNA Sequence . Zug, Switzerland: Informa . 1 (5): 291–302. doi :10.3109/10425179109020785 . ISSN 1940-1736 . OCLC 474190174 . PMID 1799681 .
—— (February 25, 1995). "An overabundance of long oligopurine tracts occurs in the genome of simple and complex eukaryotes" . Nucleic Acids Research . Oxford, UK: Oxford University Press . 23 (4): 689–695. doi :10.1093/nar/23.4.689 . ISSN 0305-1048 . PMC 306739 . PMID 7899090 .
—— (1998). "Tracts of adenosine and cytidine residues in the genomes of prokaryotes and eukaryotes". DNA Sequence . Zug, Switzerland: Informa. 8 (6): 375–383. doi :10.3109/10425179809020898 . ISSN 1940-1736 . PMID 10728822 .
Protein structure
Behe, Michael J.; Englander, S. Walter (July 1978). "Sickle hemoglobin gelation. Reaction order and critical nucleus size" . Biophysical Journal . Cambridge, MA: Cell Press . 23 (1): 129–145. Bibcode :1978BpJ....23..129B . doi :10.1016/S0006-3495(78)85438-1 . ISSN 0006-3495 . PMC 1473549 . PMID 667302 .
——; —— (September 5, 1979). "Mixed gelation theory. Kinetics, equilibrium and gel incorporation in sickle hemoglobin mixtures". Journal of Molecular Biology . Amsterdam: Elsevier . 133 (1): 137–160. doi :10.1016/0022-2836(79)90254-7 . ISSN 0022-2836 . PMID 93643 .
——; —— (September 18, 1979). "Quantitative assessment of the noncovalent inhibition of sickle hemoglobin gelation by phenyl derivatives and other known agents". Biochemistry . Washington, D.C.: American Chemical Society. 18 (19): 4196–4201. doi :10.1021/bi00586a025 . ISSN 0006-2960 . PMID 486417 .
——; Lattman, Eaton E.; Rose, George D. (May 15, 1991). "The protein-folding problem: the native fold determines packing, but does packing determine the native fold?" . Proceedings of the National Academy of Sciences of the United States of America . Washington, D.C.: National Academy of Sciences . 88 (10): 4195–4199. Bibcode :1991PNAS...88.4195B . doi :10.1073/pnas.88.10.4195 . ISSN 0027-8424 . PMC 51625 . PMID 2034665 .
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